What is the Ultimate Compatibility File?

The Ultimate Compatibility File (or UCF) is a specialized genetic data file formatted to match a typical 23andMe raw data layout. It includes about 600,000 selected genetic markers, mirroring the data structure and size most third-party platforms support. This makes it easy to use your sequencing results with genealogy sites, ancestry analysis tools, health trait platforms, and other third-party services.

Although the UCF is derived from high-coverage 30× whole genome sequencing, it does not include your full genome. Instead, it presents the specific subset of data that aligns with what 23andMe would provide.

Frequently Asked Questions

How many data points are in the Ultimate Compatibility File?
The UCF includes roughly 600,000 genetic markers, chosen to match standard genotyping arrays used by popular services.

Does the UCF include my entire genome?
No. The file mirrors the size and format of a 23andMe file and includes only selected variants, not your full genome data.

Why should I use the Ultimate Compatibility File?
Sequencing’s raw files such as FASTQ or VCF can be too large or formatted in a way that third-party sites cannot accept. The UCF solves this by providing a compatible and streamlined text file that you can easily upload to genealogy or analysis platforms.

Which third-party platforms accept the Ultimate Compatibility File?
Any platform that accepts uploads in 23andMe format will work with the UCF. This includes services like GEDmatch, openSNP, WikiTree, Promethease, and others.

Can I still access my full raw data separately?
Yes. You can still download and use your full raw sequencing files for advanced analysis or backup. The UCF is just an additional option for compatibility.

How do I request or access the UCF?
Once your sequencing is complete, the UCF will be listed under Files in your account. Just choose the UCF for download. If you need help, our support team is ready to assist.

What support is available if I have questions about using the UCF?
If you have any questions about the Ultimate Compatibility File or using it with third-party platforms, please reach out to our support team at [email protected] for assistance.