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Genotyping vs. Sequencing: Why method matters

Most DNA tests like 23andMe or AncestryDNA use a method called "genotyping." It's useful for ancestry and some basic health traits, but it only examines about 0.1% of your genetic code. Whole Genome Sequencing is the world’s most advanced genetic testing that reads your complete DNA, including all ~30,000 genes and all chromosomes end-to-end. Why this matters: Rare genetic conditions, medication responses, and inherited disease risks often show up in the genes that genotyping skips. If previous DNA tests haven't answered your questions, it's likely because they weren't looking at enough of your genome. We analyze everything. Once. Then we help you understand what it means.

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GeneCondition# of Genetic Variants Analyzed
BRCA 1/2Breast, Ovarian, Other Cancers23,9753
KCNQ1Preventable Sudden Death, SIDS4,6770
CFTRCystic Fibrosis2,71628
RYR1Preventable Reaction to Anesthesia3,8390
How do we get these numbers?
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Our whole genome sequencing obtains information on your entire genome of more than 3 billion genetic variants

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100% of your DNA data is vital for evaluating your genetic risk for diseases and adverse reactions to medical treatments.

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Get actionable health guidance based on your complete genetic profile. Understand your risks now and as research evolves.

23andMe is a registered trademark of 23andMe, Inc. The use of the name and logo are for compatibility information only and does not imply approval or endorsement of Sequencing.com by 23andMe, Inc.

One test. Health intelligence that grows over time.

New genetic discoveries happen every month, revealing new connections between your genes and your health. With an optional Health Scan subscription, we automatically check your DNA against these new findings and send you personalized insights as science advances. One DNA sequencing test. Answers that keep getting better.

Hand holding a whole genome sequencing vial while a sample is being inserted.
Hand holding a whole genome sequencing vial while a sample is being inserted.

A simple cheek swab is all it takes.

Getting your genome sequenced is as easy as brushing your teeth. No appointments, no jabs, no spitting. 1. We mail you your DNA kit 2. You gently swab your cheek for 2 minutes 3. Place the prepaid package in the mail and you’re done Safe for all ages, from newborns to adults.

Advanced technology. Surprisingly accessible.

The first human genome took 13 years and $3 billion to sequence. The information from the Human Genome Project has allowed us to better diagnose disease, detect certain diseases earlier, and make life-saving improvements in preventive medicine. Thanks to rapid advancements in technology over the last 20 years, the cost of Whole Genome Sequencing is now within reach for people who want to have better control of their health and wellness.

Digitized image of a double helix.
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Start with our DNA Day Rare Disease Special WGS Bundle, or explore a range of tailored bundles designed to provide insights across key health areas. Discover the bundle that’s right for you!

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Rare Disease Month Special Bundle

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Bundle Includes

  • Easy-To-Use DNA Collection Kit
  • 30x Whole Genome Sequencing
  • Unlimited Access To Your Genetic Data
  • Privacy Forever Protection Of Your Data
  • 1 Month Premium Genome Plan
  • Advanced AnalysisAdvanced Genetic Analysis & Insights
Full Access To All Data
Full Access To All Raw Data & Analyzed Data

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Obtains data on around 3 billion positions within your genome (100% of your genome). Also includes the ability to download your raw genome data files for no additional fee. This includes FASTQ, BAM and VCFs covering all genetic variations: Single Nucleotide Polymorphisms (SNPs), Insertions and Deletions (INDELs), Structural Variations (SVs), Copy Number Variations (CNVs) and Mitochondrial Heteroplasmy (MITO).

Ready to Get Sequenced?

Start with our DNA Day Rare Disease Special WGS Bundle, or explore a range of tailored bundles designed to provide insights across key health areas. Discover the bundle that’s right for you!

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