Due to the urgency of the rapidly spreading coronavirus pandemic, Sequencing.com is making this report free for a limited time.
|Report Section||Relevancy||Information Provided|
|Risk of Infection||Exposure||Your genetic risk of becoming infected by the coronavirus|
|Prognosis||Infection||Your genetic risk of a severe, potentially life-threatening, infection (if you are infected)|
|Treatment||Both Exposure and Infection||Your genetic risk of experiencing a harmful reaction to medications that may be used to either prevent infection (known as 'post-exposure prophylaxis') or treat infection|
|Non-Genetic Factors||Both Exposure and Infection||Your non-genetic risk of becoming infected and experiencing a more severe infection|
|Actionable Insights||Both Exposure and Infection||Straightforward information you can use to make more informed decisions about avoiding exposure and surviving infection|
|Real-Time Outbreak Tracking||Monitoring||maintain awareness of global and local outbreaks in real-time|
|Latest News||Monitoring||stay up-to-date on the latest insights and health guidance|
Once your DNA data is stored in your Sequencing.com account, all you need to do is click the report's 'Start' button.
If your DNA data is not already stored in your account, you can either import your data from a DNA test you've already taken (such as from 23andMe or AncestryDNA) or you can order one of our DNA tests.
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|Our Universal DNA Compatibility enables this report to work with DNA data from almost any genetic test||Our clinical-grade 30x Whole Genome Sequencing test obtains data on 100% of your genome. It is the only test that provides enough genetic data for the Comprehensive version of this report.|
|For example, DNA data from any of the following test providers will work with this report: 23andMe, Ancestry, MyHeritage, FamilyTreeDNA, Vitagene, Dante Labs, Nebula Genomics, Veritas, Helix and most other DNA test providers.||DNA tests performed by 23andMe, Ancestry, MyHeritage and similar companies test less than 0.1% of your genome. Their tests provide enough data for the Free Report but do not provide the genetic data required for the Comprehensive Report.|
|Free for everyone||Available to Members of Sequencing.com||Included with Sequencing.com's Whole Genome Sequencing test|
|Analysis of your DNA using almost any DNA test||Everything included in the Free version||Everything in the Plus version|
|Personalized report on how your genes may impact your health risk from the coronavirus||Additional insights about your genetic risk from coronavirus||Full genetic analysis for all genes known to impact coronavirus risk|
|Insights about personalized prevention||Includes analysis of changes in genes that are not tested by 23andMe, AncestryDNA, MyHeritage, FamilyTreeDNA or any similar test|
|Updated on a regular basis whenever there's new research pertaining to coronavirus risk|
|Real-Time Monitoring of the outbreak|
|Up-to-Date News about coronavirus-related health insights and prevention tips|
Powered by our Universal DNA Compatibility technology, this report is compatible with data from most genetic tests.
|Test Compatibility||Format Compatibility||Variant Compatibility||Reference Genome Compatibility|
|Whole Genome Sequencing||FASTQ and FQ||SNP / SNV
(Single Nucleotide Variants)
|hg38 / GRCh38|
|Exome Sequencing||FASTA and FA||INDEL
(Insertion Deletion Variants)
|hg19 / GRCh37|
|Ultimate DNA Test||BAM||hg18 / GRCh36|
|23andMe||SAM||hg17 / GRCh35|
|Dante Labs||Genome VCF (gVCF and GVCF)|
|Genes for Good||CSV|
|HomeDNA||gz and zip compressed files|
|FTDNA||almost all other genetic data formats|
|New Amsterdam Genomics|
|almost all other genetic tests|
Compare to 23andMe, Ancestry and similar that test less than 0.1% of your genome.
|Ultimate DNA Test||Whole Genome Sequencing|
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|Amount of genome tested||1%||100%|
|Technology||Genotyping Microarray||Clinical-Grade 30x Genome Sequencing|
|Coronavirus Report Version||Plus Report||Comprehensive Report|
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The blog post Your DNA and COVID-19, written by Dr. Brandon Colby MD, Sequencing.com's Founder, provides an overview of the Coronavirus DNA Health Report including why and how we created the DNA analysis for this report.
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Tang N. et al. Lack of support for an association between CLEC4M homozygosity and protection against SARS coronavirus infection. Nat Genet 39: 691–2 (2007). doi: 10.1038/ng0607-691.
Chan V. S. et al. Homozygous L-SIGN (CLEC4M) plays a protective role in SARS coronavirus infection. Nat Genet. 38: 38-46 (2006). doi: 10.1038/ng1698.
He J. et al. Association of SARS susceptibility with single nucleic acid polymorphisms of OAS1 and MxA genes: a case-control study. BMC Infect Dis 6:106 (2006). doi: 10.1186/1471-2334-6-106.
Wei-Ju C. et al. Nasopharyngeal Shedding of Severe Acute Respiratory Syndrome—Associated Coronavirus Is Associated with Genetic Polymorphisms, Clinical Infectious Diseases. 42(11): 1561-9 (2006). doi: 10.1086/503843.
Imai Y. et al. Angiotensin-converting enzyme 2 protects from severe acute lung failure. Nature 436: 112–6 (2005). doi: 10.1038/nature03712.
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Gabriella A. et al. Fatal Severe Acute Respiratory Syndrome Is Associated with Multiorgan Involvement by Coronavirus. J Infect Dis. 191(2):193-7 (2005). doi: 10.1086/426870.
Hofmann H. et al. Susceptibility to SARS coronavirus S protein-driven infection correlates with expression of angiotensin converting enzyme 2 and infection can be blocked by soluble receptor. Biochem. Biophys. Res. Commun. 319: 1216–21 (2004). doi: 10.1016/j.bbrc.2004.05.114.
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