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Ozempic and GLP-1 Agonists

Developed by PGxAI

This report provides personalized genetic insights on how DNA influences weight-loss medication response, metabolism, and side effects, helping optimize treatment strategies for safer, more effective results.

$99 per genome

Ozempic and GLP-1 Agonists DNA Genetic Report

Discover Your Genetic Blueprint for Effective Weight Management

Welcome to a new era of personalized weight loss. Our Ozemic and GLP-1 PGx report dives deep into your DNA to illuminate how your unique genetic makeup can influence your response to today’s leading weight-loss medications—such as Wegovy, Ozempic, Saxenda, Mounjaro, Contrave, and more. Armed with the latest scientific findings, you’ll gain valuable insights that can guide more tailored, effective, and safer weight-loss strategies in consultation with your healthcare provider.

Example response to weight-reduction substances based on a person's genes.

What You’ll Learn

1. Medication Response & Efficacy

Uncover how genetic variations in key receptors and enzymes—such as GLP1R, GIPR, FASN, and LEPR—can affect your sensitivity to popular obesity treatments (e.g., GLP-1 agonists, combination therapies, and more).

2. Personalized Weight-Loss Strategies

Explore how differences in genes like TAAR1, DRD2, or PCSK1 could alter your appetite regulation, metabolic rates, and overall response to specific medications, giving you the power to make more targeted lifestyle changes.

3. Genetic Variants & Side Effects

Understand how certain genetic profiles may increase or reduce the likelihood of medication side effects—such as gastrointestinal issues, altered mood, or less-than-expected weight loss—so you and your doctor can make more informed choices.

4. Lifestyle & Coexisting Factors

Learn how age, liver/kidney function, or concurrent medications can intersect with your genetics to influence how obesity drugs work in your body.

Comprehensive Report Coverage

1.    GLP-1 Agonists

  Wegovy, Ozempic, Saxenda: How genes like GLP1R, ARRB1, and TCF7L2 influence appetite suppression and blood sugar control.

2.    Dual GIP & GLP-1 Therapies

Mounjaro, Zepbound: The role of GIPR and TCF7L2 in dual-receptor treatments and why some people respond more robustly.

3.    Fat Absorption Blockers

Xenical, Alli: Discover how FASN, CYP3A4, and CYP3A5 interplay with orlistat’s fat-inhibiting action.

4.    Combination Appetite Suppressants

Qsymia: Learn how genes like GRIK1, PLXNA4, and INSR can affect phentermine/topiramate efficacy.

5.    Opioid Antagonist & Antidepressant Combo

Contrave: Explore how ANKK1 and DRD2 may impact cravings, appetite control, and dopamine-related reward pathways.

6.    Traditional Sympathomimetics

Adipex-P, Lomaira: Assess the role of TAAR1, COMT, and HTR2C in phentermine responsiveness.

7.    Targeted MC4R Agonists

Imcivree: Understand the significance of POMC, PCSK1, and LEPR in rare genetic forms of obesity.

Key Features

Cutting-Edge Pharmacogenomics

We use high-resolution array-based assays and advanced bioinformatics to identify key genetic variants with >99% analytical sensitivity and specificity.

Personalized Insights, Clear Explanations

Each result is presented in straightforward language, helping you see how your genes may influence medication absorption, metabolism, and overall outcomes.

Evidence-Based Recommendations

Our report integrates the latest scientific studies, providing detailed references so you can dig deeper or discuss specifics with your healthcare provider.

Holistic Considerations

Genetics is just one piece of the puzzle. We highlight additional factors—such as age, organ health, and lifestyle—to give you a well-rounded perspective on weight management.

Expert Support and Industry Partnerships

This report was developed by PGxAI in collaboration with top universities and supported by InterSystems, ensuring robust data analytics and innovative genomic insights.

Why Your DNA Matters

Not all weight-loss plans fit everyone. Genetic variants can significantly impact how you respond to medications—both in terms of effectiveness and potential side effects. By examining these genetic differences, our Obesity PGx report helps you and your healthcare provider make more precise decisions, fine-tuning your medication plan for maximum benefit.

Safe & Informed Choices

This unique DNA report is designed to empower you with knowledge, not replace professional medical judgment. Always consult with your healthcare provider to interpret results and tailor your treatment. Please note that our software has not been reviewed by the FDA or EMA and is for educational purposes only.

Join the Future of Precision Medicine

Embrace a proactive approach to weight management. Harness the power of your unique genetic code to optimize treatment and increase your potential for success. Take the first step towards personalized healthcare today.

Sample Report