DNA App Spotlight: Detoxify Your Body, Better Skin Care, and Personalized Fitness

GeneInformed DNA apps pair original research with up-to-date scientific literature and use bioinformatic tools to provide recommendations based on your DNA. This spotlight covers three GeneInformed apps available in the Partner Marketplace.

App Spotlight 1: Genetic Detoxification

Your body works continuously to defend you against toxins in your environment. From the foods you eat to the chemicals you are exposed to, health hazards can be found almost anywhere. Your unique genetics influence whether you are more or less efficient at processing certain toxins. A predisposition to a deficiency in detoxification pathways can allow toxins to accumulate, potentially contributing to health issues over time.

The Genetic Detoxification report from GeneInformed analyzes dozens of your genes and enzymes responsible for metabolizing toxic agents and chemicals. Based on your results, the report provides personalized insights and recommendations to help optimize your body's ability to neutralize and eliminate harmful substances.

Inside the Genetic Detoxification report, you will find insights on:

• Phase I detoxification enzymes, which activate or deactivate toxins in the liver
• Phase II detoxification enzymes, which conjugate and prepare toxins for elimination
• Antioxidant capacity and oxidative stress markers
• Heavy metal sensitivity and methylation pathways
• Personalized lifestyle and dietary recommendations to support your detox pathways

App Spotlight 2: Skin Genes

Your skin is the largest organ in the human body, accounting for 6 to 10 percent of the average adult's body weight. It protects you from the elements, defends against bacteria and microbes, and regulates body temperature. Your genetics play a meaningful role in how your skin ages and how it responds to different care routines.

The Skin Genes report from GeneInformed helps you build a skin care routine personalized to your genetic makeup. The report provides cosmetic, lifestyle, and other recommendations specific to your DNA. Inside the Skin Genes report, you will learn about:

• Elasticity and wrinkling, including genetic tendencies to form wrinkles or sagging skin
• Hydration and moisture retention based on your genetic profile
• Sun sensitivity and UV damage risk
• Antioxidant needs and free radical response
• Inflammation markers relevant to skin conditions
• Personalized product and lifestyle recommendations

App Spotlight 3: Gene-In-Form Personalized Fitness

Research suggests genetics can play a meaningful role in athletic performance and training response. Whether you are an amateur athlete or compete at a higher level, training, rest, and rehabilitation are areas where your unique genetics make a difference.

The Gene-In-Form Personalized Fitness report from GeneInformed uses your DNA to help maximize your athletic potential and limit injury risk. Inside the report, you will learn about your body's inherited advantages, disadvantages, and responses to the stresses of athletic training. Topics covered include:

• Muscle composition, including your muscle fiber type, lactate profile, and likely response to training
• Respiratory and circulatory markers, including VO2 max and genetic indicators for aerobic fitness
• Elevated injury risk, including risk of ACL and meniscus injuries
• Recovery and inflammation response
• Personalized training and nutrition recommendations based on your genetic profile

How to Access These Reports

If you have already taken a DNA test from 23andMe, AncestryDNA, MyHeritage, or another provider, you can upload your raw DNA data to Sequencing for free and run any of these reports from the Partner Marketplace. For the most complete data to work with, Sequencing offers clinical grade whole genome sequencing that reads 100% of your DNA across all of your over 30,000 genes.