Wellness and Longevity DNA Analysis App and Genetic Health Report

Wellness and Longevity

Predict     Prevent     Prevail

Transform your DNA into clear solutions for better health.

Created by physicians and clinical geneticists, this app analyzes your DNA and provides a straightforward, actionable report focused on protecting and optimizing your health.

 

Predict

The app analyzes your genetic risk of a wide range of preventable disease. You'll learn what path your genes are putting you on for diseases such as cancer and heart disease.

Prevent

Knowing your risk means having the chance to lower it. The app provides you with an actionable report that provides clear solutions for optimizing your health.

Prevail

Be proactive and use the information obtained from your genes to protect your health.

 

Sample Report

This app analyzes your DNA and provides insights about health.

If your DNA data is not already stored in your Sequencing.com account, you can either import your data from a DNA test you've already taken or you can order a DNA test.

You've already taken a DNA test

   

You need a DNA test

Upload your DNA data     Order a DNA test
       
Our Universal DNA Compatibility enables this app to work with DNA data from almost any DNA test.     Our clinical-grade 30x Whole Genome Sequencing test obtains data on 100% of your genome.

Use the Upload Center to upload and use your DNA test or genome sequencing data.

Powered by our Universal DNA Compatibility technology, this report is compatible with data from most genetic tests.

 

Test Compatibility   Format Compatibility   Variant Compatibility   Reference Genome Compatibility
Whole Genome Sequencing   FASTQ and FQ   SNP / SNV
(Single Nucleotide Variants)
  hg38 / GRCh38
Exome Sequencing   FASTA and FA   INDEL
(Insertion Deletion Variants)
  hg19 / GRCh37
Ultimate DNA Test   BAM       hg18 / GRCh36
23andMe   SAM       hg17 / GRCh35
AncestryDNA   CRAM        
MyHeritage   VCF        
Dante Labs   Genome VCF (gVCF and GVCF)        
Nebula Genomics   TXT        
Genes for Good   CSV        
Living DNA   TAB        
HomeDNA   gz and zip compressed files        
FTDNA   almost all other genetic data formats        
Silverberry Genomix            
Toolbox Genomics            
Full Genomes            
Color            
New Amsterdam Genomics            
24Genetics            
Vitagene            
Helix            
Genos            
tellmeGen            
GSA            
Axiom            
almost all other genetic tests

This DNA analysis app is optimized for Sequencing.com's Whole Genome Sequencing test and Ultimate DNA Test.

Compare to 23andMe, Ancestry and similar that test less than 0.1% of your genome.

 

    Ultimate DNA Test   Whole Genome Sequencing
    BUY NOW   BUY NOW
         
Discounted Price   $69  $189   $399  $599
         
Amount of genome tested   1%   100%
         
Technology   Genotyping Microarray   Clinical-Grade 30x Genome Sequencing
         
Also Includes  

Silver Membership to Sequencing.com

 

Silver Membership to Sequencing.com

Wellness & Longevity Health Analysis

Healthcare Pro Report

Rare Disease Screen Analysis

Two sample genetic reports are provided.

  • The genetic report in the 'Overview' tab was generated when this app analyzed Whole Genome Sequencing (WGS) data.
  • The genetic report below was generated when this app analyzed DNA data from 23andMe.

This app analyzes a wide range of preventable diseases, conditions and medication reactions including:

  • cancer, including  skin,  breast,  colon,  and  other  forms  of  cancer

  • heart disease and heart attack

  • harmful medication reactions

  • optimal medication dosage

  • preventable causes of sudden death

  • multiple sclerosis

  • blood clot disorders

  • bleeding abnormalities

A personalized plan of disease prevention may allow you and your doctor to significantly reduce your risk of a large number of diseases and even prevent many from ever forming.

Analysis of your genes may also allow you and your doctor to understand how your body will react to a wide range of medications so that he or she can prescribe those that are likely to be most effective and least harmful.

Disease Prevention

Learn your risk for, and ways to personalize your prevention of, dozens of common diseases such as 

  • Cancer,  including  skin,  breast,  colon,  and  other  forms  of  cancer
  • Heart disease, including an extensive screening for preventable causes of  arrhythmias  (an  abnormal  heartbeat  that  can  lead  to  sudden death in adults, children, and even babies), coronary artery disease and heart attack
  • Obesity, multiple sclerosis, blood clot disorders, bleeding abnormalities and more.

Medication Guidance

Discover the most effective medications and the optimal dosing based on your genes, as well as what medications to avoid because they are likely to cause harmful side effects.

Outsmart Your Genes

Genes play a significant role in determining who you are.  They dictate not only your physical appearance and many of your personality traits but also your risk for disease and how your body will respond to certain medications. In addition, your genes determine your risk of passing on diseases to your children.  

For most common diseases, such as many forms of cancer, heart disease, autoimmune diseases, diabetes and obesity, genes are just one of the factors that determine your risk.  Non-genetic factors, such as your lifestyle (what specific foods and beverages you consume, the amounts and types of exercises you perform), the medications you take, and the medical screening procedures you have (colonoscopies, full body skin exams, etc.) may also contribute to overall disease risk and prevention.

This app utilizes proprietary technology for genetic analysis and report generation.

This app uses Sequencing.com's comprehensive database of genotypes and their related phenotypes. This includes relational data pertaining to phenotypes, algorithms to calculate risk (for multifactorial phenotypes) and carrier status (for monogenic phenotypes) and the ability to generate dynamic genetic reports focusing on straightforward, useful insights.

A multifactorial algorithm is used to assess risk of melanoma, heart disease, osteoarthritis and osteoporosis.

A monogenic algorithm is used to assess all other phenotypes. The results of monogenic analysis are one of the following:

Custom

  • Custom results may be provided for specific genotypes. These customized results are obtained from literature reviews that investigated of made note of a phenotype for a specific genotype. This may include information about penetrance.

Not a carrier

  • No phenotype-causing alleles detected

Carrier but not affected

  • One phenotype causing allele detected for
    • an autosomal recessive phenotype
    • an X-linked recessive phenotype (if the genetic data is from a female)

Likely affected

  • Two phenotype-causing alleles detected for an autosomal recessive phenotype
  • One phenotype-causing allele detected for an autosomal dominant phenotype
  • One phenotype-causing allele detected for an X-linked dominant phenotype
  • One phenotype-causing allele detected for an X-linked recessive phenotype (when the phenotype has been found to be detectable even in heterozygous females)

Do I need to do anything to the file containing my genetic data before it is analyzed by this app?

Good news... the app does everything for you.

All you need to do is either upload or import the file containing your genetic data into your Sequencing.com account. Start the app, select the file and the app will handle do everything else.

23andMe data can be uploaded or imported directly from 23andMe (via the Upload Center) while Ancestry.com, Family Tree DNA and The Genographic Project data can be obtained from those services and then uploaded to your account at Sequencing.com. You don't need to do anything to the file you obtain from these services... just upload the file to your secure account at Sequencing.com and then you can use it to power most apps.

Both whole and exome sequencing data can be provided unaligned (such as in FASTQ or FASTA formats), aligned but without variant calling (such as BAM or SAM formats) or in VCF, CRAM or AVRO formats.

 

Where do I indicate sex and reference genome?

Some more good news... the app does this as well. It utilizes an advanced automated approach to determine sex and reference genome (if the file format is downstream of alignment).

 

What do the question marks and dashes represent in the 'My Genetic Makeup' column of this table?

??
Two question marks are used when your genetic data file did not contain any data on this specific genetic variant and therefore the data was not tested for and is 'Unknown'. Two question marks are used because each person's DNA contains two copies of that genetic variant so there is one question mark for each copy of the genetic variant in your DNA.
 
?
A single question mark will appear when your genetic data file did not contain any data on this specific genetic and DNA commonly only contains a single copy of that genetic variant. 
For example, all variants on the mitochondrial chromosome (Chromosome "M") exist as a single copy because DNA only contains a single copy of the mitochondrial chromosome. This is different from most chromosomes, which appear duplicate (there are two copies of chromosome 1, two copies of chromosome 2, etc.). If the variant is on a chromosome that there is only a single copy of and there is no data on that variant in the data file then only a single question mark will appear.
 
--
Two dashes are used if your genetic data file does include information about this specific genetic variant but the data is a 'No Call.' A 'No Call' means the lab that generated the file determined that the variant's test result did not pass quality control. A 'No Call' may also appear when Sequencing.com's additional quality control determines a variant's result is not reliable and may provide inaccurate results. Sequencing.com has implemented this additional quality control to ensure that only the highest quality genetic data is analyzed by apps.
Two dashes are used instead of question marks because the genetic data file does contain data on that variant but the variant's results are not reliable.
 
-
A single dash is used when the variant's results are not reliable (ie the test result for that variant fails quality control) and DNA contains only a single copy of that variant. For example, all variants on the mitochondrial chromosome that are tested for by a genetic test but don't pass quality control have a single dash as the variant's result.

$69  $99

Icon for the Healthcare Pro DNA Analysis App that provides genetic interpretation of genome data with a focus on healthcare professionals for identifying personalized genetic risk of diseases and medication rxns (pharmacogenomics and pharmacogenetics).

Healthcare Pro

Genetic analysis and actionable reports for the practicing healthcare professional. Includes assessment and straightforward information for common, preventable diseases and medication reactions.

 

Icon for the Rare Disease Screen DNA Analysis App that provides genetic interpretation for more than 1,000 orphan and rare diseases, syndromes and traits using genome and DNA test data from 23andMe, AncestryDNA, Helix, MyHeritage and FamilyTreeDNA.

Rare Disease Screen

Analyzes more than 1,200 rare diseases, syndromes conditions and traits. Determines whether a person is a carrier of, or likely affected by, one or more rare diseases.  Useful for comprehensive analysis of genetic data as well as preconception screening (to identify diseases a person may carry and may pass on to their children).

View the full list of rare diseases, conditions and traits

The genetic analysis and statements that appear in this app have not been evaluated by the United States Food and Drug Administration. The Sequencing.com website and all software applications (Apps) that use Sequencing.com's website, as well as Sequencing.com's open Application Programming Interface (API), are not intended to diagnose, treat, cure, or prevent any disease.