Created by physicians and clinical geneticists, this app analyzes your DNA and provides a straightforward, actionable report focused on protecting and optimizing your health.
The app analyzes your genetic risk of a wide range of preventable disease. You'll learn what path your genes are putting you on for diseases such as cancer and heart disease.
Knowing your risk means having the chance to lower it. The app provides you with an actionable report that provides clear solutions for optimizing your health.
Be proactive and use the information obtained from your genes to protect your health.
Two sample genetic reports are provided.
cancer, including skin, breast, colon, and other forms of cancer
heart disease and heart attack
harmful medication reactions
optimal medication dosage
preventable causes of sudden death
blood clot disorders
Analysis of your genes may also allow you and your doctor to understand how your body will react to a wide range of medications so that he or she can prescribe those that are likely to be most effective and least harmful.
Learn your risk for, and ways to personalize your prevention of, dozens of common diseases such as
Discover the most effective medications and the optimal dosing based on your genes, as well as what medications to avoid because they are likely to cause harmful side effects.
Genes play a significant role in determining who you are. They dictate not only your physical appearance and many of your personality traits but also your risk for disease and how your body will respond to certain medications. In addition, your genes determine your risk of passing on diseases to your children.
For most common diseases, such as many forms of cancer, heart disease, autoimmune diseases, diabetes and obesity, genes are just one of the factors that determine your risk. Non-genetic factors, such as your lifestyle (what specific foods and beverages you consume, the amounts and types of exercises you perform), the medications you take, and the medical screening procedures you have (colonoscopies, full body skin exams, etc.) may also contribute to overall disease risk and prevention.
*Upload your genetic data at the Upload Center. If you don't yet have genetic data, don't worry! You can use one of our fun sample genomes. Just start the app and select a sample genome.
Import or upload your DNA data to get started.
This app is compatible with DNA data in any format. You do not need to convert your data into a different format or modify it in any way.
This includes data files from 23andMe, Ancestry and similar genotyping DNA tests as well as genome sequencing files (FASTQ, BAM, VCF) from Sequencing.com, Nebula Genomics, Dante Labs and all other sequencing providers.
The ability for this app to analyze each trait, disease and medication reaction will depend upon the amount of genetic data in your genetic data file. If there is not enough genetic data in your file then some traits, diseases or medication reactions may not be able to be fully analyzed or may not be able to be analyzed at all. The results will indicate if this occurs. For example, if there is no genetic data for a specific disease to be analyzed then the result will indicate 'Not enough data to analyze.' This is more likely to occur if your genetic data file is from a company or laboratory that uses DNA microarray technology for their genetic testing, such as AncestryDNA, Family Tree DNA and MyHeritage.
|Test Compatibility||Format Compatibility|
|Whole Genome Sequencing (WGS)||FASTQ|
|Sequencing.com Ultimate DNA Test||SAM|
|23andMe||gVCF (genome VCF)|
|AncestryDNA||VCF (regular VCF)|
|FamilyTreeDNA (FTDNA)||gz and zip compressed files|
|Genes For Good (GFG)||almost all other genetic data formats|
|New Amsterdam Genomics|
|almost all other genetic tests|
You can still use this app. When you sign into the app for the first time you'll have the option to select from a list of sample genetic data if you don't have your own. All of the sample data are from real individuals so the analysis, results and genetic report are real, too.
You can use genetic data from almost any laboratory genetic test. This includes:
Please note that the ability for this app to analyze each trait, disease and medication reaction will depend upon the amount of genetic data in your genetic data file. If there is not enough genetic data in your file then some traits, diseases or medication reactions may not be able to be fully analyzed or may not be able to be analyzed at all. The results will indicate if this occurs. For example, if there is no genetic data for a specific disease to be analyzed then the result will indicate 'Not enough data to analyze.' This is more likely to occur if your genetic data file is from a company or laboratory that uses DNA microarray technology for their genetic testing, such as Ancestry.com and National Geographic.
Good news... the app does everything for you.
All you need to do is either upload or import the file containing your genetic data into your Sequencing.com account. Start the app, select the file and the app will handle do everything else.
23andMe data can be uploaded or imported directly from 23andMe (via the Upload Center) while Ancestry.com, Family Tree DNA and The Genographic Project data can be obtained from those services and then uploaded to your account at Sequencing.com. You don't need to do anything to the file you obtain from these services... just upload the file to your secure account at Sequencing.com and then you can use it to power most apps.
Both whole and exome sequencing data can be provided unaligned (such as in FASTQ or FASTA formats), aligned but without variant calling (such as BAM or SAM formats) or in VCF, CRAM or AVRO formats.
Some more good news... the app does this as well. It utilizes an advanced automated approach to determine sex and reference genome (if the file format is downstream of alignment).
Nexus® includes a comprehensive database of genotypes and their related phenotypes, relational data pertaining to phenotypes, algorithms to calculate risk (for multifactorial phenotypes) and carrier status (for monogenic phenotypes) and the ability to generate dynamic genetic reports that are focused on empowering the individual.
A multifactorial algorithm is used to assess risk of melanoma, heart disease, osteoarthritis and osteoporosis.
A monogenic algorithm is used to assess all other phenotypes. The results of monogenic analysis are one of the following:
Genetic analysis and actionable reports for the practicing healthcare professional. Includes assessment and straightforward information for common, preventable diseases and medication reactions.
Analyzes more than 1,200 rare diseases, syndromes conditions and traits. Determines whether a person is a carrier of, or likely affected by, one or more rare diseases. Useful for comprehensive analysis of genetic data as well as preconception screening (to identify diseases a person may carry and may pass on to their children).
The genetic analysis and statements that appear in this app have not been evaluated by the United States Food and Drug Administration. The Sequencing.com website and all software applications (Apps) that use Sequencing.com's website, as well as Sequencing.com's open Application Programming Interface (API), are not intended to diagnose, treat, cure, or prevent any disease.