APOE4 test
$39 / use

APOE4 Test | Brain Health Genetic Analysis

APOE4 test

APOE4 Test: APOE Gene Test

Comprehensive Analysis of the APOE Gene for Protecting Brain Health

The APOE Brain Health DNA Test Analysis includes:

  • An analysis of your APOE gene

    • Includes APOE genotype status (ε2, ε3 or ε4)

  • An assessment of health risks and benefits based on your APOE gene analysis

    • Includes an assessment of risk of Alzheimer's disease

  • A comprehensive review of the latest research on the functions and biochemistry of the APOE gene

  • Detailed diet, lifestyle, and supplement recommendations based on SelfDecode’s Proprietary Biochemical Analysis and experience with over 1,000 clients

  • A Personalized APOE Diet Guide to help reduce the non-genetic risk of Alzheimer's based on your APOE gene version (known as your APOE 'epsilon genotype')


APOE2 (ApoE-ε2) Gene Variant

Contrary to popular belief, the ApoE-ε2 allele actually decreases the function of ApoE. Although this variant of ApoE-ε2 is neuroprotective (decreased risk of Alzheimer's disease), it does confer health risks of its own.

If your DNA is found to have the ApoE-ε2 genotype, it becomes even more important to regularly monitor blood biomarkers and live an ApoE-ε2-compatible lifestyle.

This app will identify your APOE genotype and, based on your APOE gene, you'll receive clear solutions for better health


PPAR-γ Function and The ApoE Gene

Reduced ApoE function can raise your cholesterol and make your brain more susceptible to damage. The ApoE-ε4 genotype results in significantly lower function and levels of the ApoE protein.

The PPAR-γ protein is responsible for controlling the production of the ApoE proteins and several activators of PPAR-γ have been proposed as preventive or therapeutic measures for Alzheimer’s.


Sample APOE4 Test Genetic Report

Stay Up-To-Date With DNA Research

Sequencing Education Center

Sequencing's new Education Center provides articles on genetic research, DNA testing technologies, and precision medicine. It's a great place to visit to stay up-to-date on the latest genetic discoveries.

For example, the Education Center contains a section on how DNA impacts the side of having a side effect from a medication. If you've ever experienced a side effect after taking medication, it may be due to your DNA.

This app analyzes your DNA data and provides personalized insights for protecting and improving brain health.

Once your DNA data is stored in your Sequencing.com account, after purchasing this DNA report simply click the app's 'Start' button and you'll receive your report in about 30 minutes.

If your DNA data is not already stored in your account, you can either import your data from a DNA test you've already taken (such as from 23andMe or AncestryDNA) or you can order one of our DNA tests.

You've already taken a DNA test
Import data img 0
Our Universal DNA Compatibility enables this app to work with DNA data from almost any genetic test including 23andMe, Ancestry, MyHeritage, FTDNA and genome sequencing.
You need a DNA test
2 kits 1
Our clinical-grade 30x Whole Genome Sequencing test obtains data on 100% of your genome.

The Ultimate DNA Test and Ultimate Genome Sequencing provide all of the data analyzed by this APOE Brain Health Report.



Ultimate DNA Test Kit

Ultimate DNA Test

Ultimate Genome Sequencing DNA Collection Kit

Ultimate Genome Sequencing

Discounted Price $69  $189 $399  $599
Amount of genome tested 1% 100%
Technology Enhanced Genotyping Microarray Clinical-Grade 30x Genome Sequencing


Silver Membership to Sequencing.com

(includes your choice of DNA analysis apps & reports)

Silver Membership to Sequencing.com

Wellness & Longevity Health Analysis

Healthcare Pro Report

Rare Disease Screen Analysis

This DNA report can analyze data from almost all DNA tests and genome sequencing services.


Test Compatibility   Format Compatibility   Variant Compatibility   Reference Genome Compatibility
Whole Genome Sequencing   FASTQ and FQ   SNP / SNV
(Single Nucleotide Variants)
  hg38 / GRCh38
Exome Sequencing   FASTA and FA       hg19 / GRCh37
Ultimate DNA Test   BAM       hg18 / GRCh36
23andMe   SAM       hg17 / GRCh35
AncestryDNA   CRAM        
MyHeritage   VCF        
Dante Labs   Genome VCF (gVCF and GVCF)        
Nebula Genomics   TXT        
Genes for Good   CSV        
Living DNA   TAB        
HomeDNA   gz and zip compressed files        
FTDNA   almost all other genetic data formats        
Silverberry Genomix            
Toolbox Genomics            
Full Genomes            
New Amsterdam Genomics            
almost all other genetic tests



  • Jonathan Ritter, PharmD, PhD (Pharmacology)
  • Nattha Wannissorn, PhD
  • Ana Aleksic MSc (Pharmacology)

The genetic analysis and statements that appear in this app have not been evaluated by the United States Food and Drug Administration. The Sequencing.com website and all software applications (Apps) that use Sequencing.com's website, as well as Sequencing.com's open Application Programming Interface (API), are not intended to diagnose, treat, cure, or prevent any disease.