APOE DNA Analysis Brain Health Alzheimer's Disease Genetic Report

APOE Brain Health DNA Report

The World's Most Comprehensive Analysis of the APOE Gene and Brain Health

The DNA report includes:

  • An analysis of your APOE gene

    • Includes APOE genotype status (ε2, ε3 or ε4)

  • An assessment of health risks and benefits based on your APOE gene analysis

    • Includes an assessment of risk of Alzheimer's disease

  • A comprehensive review of the latest research on the functions and biochemistry of the APOE gene

  • Detailed diet, lifestyle, and supplement recommendations based on SelfDecode’s Proprietary Biochemical Analysis and experience with over 1,000 clients

  • A Personalized APOE Diet Guide to help reduce the non-genetic risk of Alzheimer's based on your APOE gene version (known as your APOE 'epsilon genotype')


Sample APOE Genetic Report

$79 $59

PPAR-γ function and the ApoE gene

Reduced ApoE function can raise your cholesterol and make your brain more susceptible to damage. The ApoE-ε4 genotype results in significantly lower function and levels of the ApoE protein.

The PPAR-γ protein is responsible for controlling the production of the ApoE proteins and several activators of PPAR-γ have been proposed as preventive or therapeutic measures for Alzheimer’s.


Health Risks Associated with the ApoE-ε2 Allele

Contrary to popular belief, the ApoE-ε2 allele actually decreases the function of ApoE. Although this variant of ApoE-ε2 is neuroprotective (decreased risk of Alzheimer's disease), it does confer health risks of its own.

If your DNA is found to have the ApoE-ε2 genotype, it becomes even more important to regularly specific monitor blood biomarkers and live an ApoE-ε2-compatible lifestyle.

This app will identify your APOE genotype and, based on your APOE gene, you'll receive clear solutions for better health

Powered by Sequencing.com's Universal Compatibility technology, the APOE Brain Health DNA Report app is compatible with genetic data from all DNA tests:

Test Compatibility Format Compatibility
Whole Genome Sequencing (WGS) FASTQ
Exome Sequencing (WES) FASTA
Dante Labs BAM
23andMe SAM
AncestryDNA CRAM
MyHeritage VCF
Genes for Good GVCF (genome VCF without blocks)
Living DNA gVCF (genome VCF with blocks)
Silverberry Genomix TAB
Toolbox Genomics gz and zip compressed files
Helix almost all other genetic data formats
Nebula Genomics  
Veritas Genetics  
Human Longevity Inc (HLI)  
Oxford Nanopore  
almost all other genetic tests

Where should I get my genes tested?

You can use the raw DNA data you receive from any DNA testing company, such as 23andMe, Ancestry, FamilyTreeDNA, MyHeritage and Dante Labs. Just be aware that not every testing company will include each and every SNP analyzed by this app.

Note: False negative problems have been reported in the Ancestry data, which may give you false information about your genotype.


  • Jonathan Ritter, PharmD, PhD (Pharmacology)
  • Nattha Wannissorn, PhD
  • Ana Aleksic MSc (Pharmacology)

The genetic analysis and statements that appear in this app have not been evaluated by the United States Food and Drug Administration. The Sequencing.com website and all software applications (Apps) that use Sequencing.com's website, as well as Sequencing.com's open Application Programming Interface (API), are not intended to diagnose, treat, cure, or prevent any disease.