
Melioidosis: Antibiotic Resistance and Genetic Testing
Burkholderia pseudomallei can resist ceftazidime, polymyxin B and co-trimoxazole, and molecular tests detect both the bacterium and its resistance mutations.

MD · MBA
Physician specializing in genetic analysis and personalized preventive medicine, and author of Outsmart Your Genes.
Brandon Colby is a physician-expert in the fields of genetic analysis and Personalized Preventive Medicine. He holds an MD from the Mount Sinai School of Medicine, an MBA from Stanford University's Graduate School of Business, and a degree in Genetics from the University of Michigan.
Dr. Colby is the author of the book Outsmart Your Genes and has developed numerous technologies that improve the analysis, interpretation, and actionability of genome sequencing data. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics (ACMG), an Associate of the American College of Preventive Medicine (ACPM), and a member of the National Society of Genetic Counselors (NSGC).
Articles by Brandon Colby, MD are reviewed for accuracy by Sequencing's medical and scientific team. This page is for informational purposes and does not constitute medical advice.

Burkholderia pseudomallei can resist ceftazidime, polymyxin B and co-trimoxazole, and molecular tests detect both the bacterium and its resistance mutations.

Genetic variation that influences memory performance is mapped through quantitative trait loci, an approach applied to risk, drug targets and cognitive decline.

Explore the benefits of genetic testing for MERFF syndrome, including early diagnosis, treatment, family planning, and prenatal diagnosis. Discover advancements in next-generation…

A mutation in the MMP13 gene disrupts an enzyme needed for bone growth. MANDP1 is autosomal dominant, so each child of an affected parent has a 50% risk.

Faulty methylmalonyl-CoA mutase lets methylmalonic acid accumulate, causing failure to thrive and neurological complications. MUT sequencing pins down the subtype.

Discover the importance of genetic testing in diagnosing and managing Methylmalonic Aciduria, mut(0) type, a rare metabolic disorder, and its impact on patients' lives.

Spotted at birth, an underdeveloped outer ear prompts audiologic evaluation, imaging and gene analysis; PBX1 and RET variants appear in reported microtia cases.

COX deficiency disturbs an enzyme cells need for energy, bringing muscle weakness, developmental delays and multi-organ problems; a COX10 mutation is one reported cause.