Understanding, Diagnosing, and Using Genetic Testing for Perinatal Hemolytic Anemia
Newborns with rapid red blood cell breakdown may show jaundice, an enlarged liver and spleen, edema and breathing trouble; gene testing confirms the cause.
Brandon Colby, MD
MD · MBA
Physician specializing in genetic analysis and personalized preventive medicine, and author of Outsmart Your Genes.
About Brandon
Brandon Colby is a physician-expert in the fields of genetic analysis and Personalized Preventive Medicine. He holds an MD from the Mount Sinai School of Medicine, an MBA from Stanford University's Graduate School of Business, and a degree in Genetics from the University of Michigan.
Dr. Colby is the author of the book Outsmart Your Genes and has developed numerous technologies that improve the analysis, interpretation, and actionability of genome sequencing data. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics (ACMG), an Associate of the American College of Preventive Medicine (ACPM), and a member of the National Society of Genetic Counselors (NSGC).
Education
- BA in Genetics with Honors, University of Michigan · 2000
- MD, Mount Sinai School of Medicine · 2004
- MBA, Stanford University Graduate School of Business · 2007
Affiliations & Memberships
- Affiliate Specialist, American College of Medical Genetics and Genomics (ACMG)
- Associate, American College of Preventive Medicine (ACPM)
- Member, National Society of Genetic Counselors (NSGC)
Articles by Brandon Colby, MD are reviewed for accuracy by Sequencing's medical and scientific team. This page is for informational purposes and does not constitute medical advice.
Articles by Brandon
Understanding, Diagnosing, and Using Genetic Testing for ARMC9-related Joubert Syndrome
The molar tooth sign on MRI, along with ataxia, nystagmus and hypotonia, points to this autosomal recessive syndrome, confirmed by ARMC9 sequence analysis.
Unlocking the Mysteries of Arrhythmogenic Cardiomyopathy: Diagnosis and Genetic Testing
Healthy heart muscle is replaced by fibrous and fatty tissue in ACM, bringing palpitations, dizziness and fainting that ECG, echocardiography and MRI help assess.
ASHER: Spastic Ataxia Caused by SACS Mutations
Progressive muscle weakness, spasticity and loss of coordination from early childhood follow SACS mutations, which testing identifies in patients and carriers.
Atelis Syndrome 1: A Comprehensive Guide to Understanding, Diagnosing, and Genetic Testing
Developmental delays, intellectual disability and seizures mark this rare disorder; MRI, EEG and gene testing confirm it and inform treatment and family planning.
Peering into the Genetic Code: Understanding Atelis Syndrome 2
Atelis Syndrome 2 causes developmental delays and physical abnormalities; testing confirms the diagnosis and supports carrier, prenatal and IVF embryo screening.
Atorvastatin Efficacy: SLCO1B1, CYP3A4 and Dosing
Not everyone gets the same LDL reduction from atorvastatin; SLCO1B1, CYP3A4 and ABCG2 variants affect uptake, metabolism and the risk of muscle pain or weakness.
Unlocking the Mysteries of Atypical Cerebral Palsy: Genetic Testing and Beyond
Unusual muscle tone, jerky movements and seizures set atypical CP apart; MRI plus ACTB or ACTG1 analysis can reveal causes such as Baraitser-Winter syndrome.