Data Viewer Plus provides additional information relating to diseases, conditions, traits and medication reactions.
Upgrading to Data Viewer Plus is $4.99 per file
- You can then use Data Viewer Plus with that file as often as you want for one year.
To upgrade to Data Viewer Plus
- Start this app (the free version of Data Viewer)
- Once your data loads in your Data Viewer, click the option to upgrade to the Plus version
Data Viewer vs Data Viewer Plus
Data Viewer is free and provides technical details about your genetic data. Each genetic variant (also referred to as SNP, SNV, DIP or InDel) from your file is listed on its own row along with the bioinformatic-related data about the variant (such as the gene, chromosome number, position on the chromosome, amino acid change (if there is one), etc.
Data Viewer Plus provides all the information available in the free Data Viewer as well as information about diseases, traits, medication reactions and scientific studies. Data Viewer Plus includes:
the disease, trait or medication reaction associated with the genetic variant
an indication of whether all available scientific studies and clinical data support the association between the variant and the condition
'Pathogenic' and 'Likely Pathogenic' indicate support for the association
'Benign' and 'Likely Benign' indicate that the variant may not be associated with the condition
an indication of the amount of confidence for the Interpretation
Four stars = highest confidence that the Interpretation is correct
Half of one star = lowest confidence that the Interpretation is correct
this usually occurs when there is only one study about the association between the variant and the condition and therefore the Interpretation is based only on a single study
clickable link to each journal article that has been published about the association between the variant and the condition
clickable links that take you directly to additional information (SNPedia and ClinVar) for each variant
What data can be viewed with Data Viewer?
The data viewer allows you to view almost all types of genetic data including data from whole genome sequencing, exome sequencing and DNA microarrays. This includes genetic data files provided by laboratories and companies such as 23andMe, Ancestry.com, MyHeritage, Genes for Good, Family Tree DNA, Dante Labs, Genomics Personalized Health and Illumina.
Do I have to convert my data into a specific format before using Data Viewer?
Data Viewer is already compatible with the format that your genetic data is already in. You do not need to convert your files and instead Data Viewer. Sequencing.com's unique Universal Data Compatibility technology
enables all genetic data formats to be fully compatible with Data Viewer.
Will I be able to understand the genetic data that appears in Data Viewer and Data Viewer Plus?
Data Viewer and Data Viewer plus are designed for people who are comfortable interpreting their own raw genetic data. Interpreting your own data can become technical at times so it isn't for everyone.
If you find the data difficult to understand or simply want to learn actionable information about your genes, there are a wide range of apps in the marketplace
in the Wellness, Nutrition, Fitness, and similar categories. These apps are designed to provide clear solutions for optimizing wellness and lifestyle.
How can I get assistance understanding my genetic data? Is there anyone I can ask?
Yes, assistance is available from a certified genetic counselor. To speak with a genetic counselor, please use the Genetic Counseling app
What's the difference between Data Viewer and Data Viewer Plus?
For information about Data Viewer Plus, please click on the 'Data Viewer Plus' tab on this page.
Why are genes or genetic variants missing?
When viewing Data Viewer (and Data Viewer Plus), only the raw data contained within your genetic data file is displayed. If a gene wasn't tested for then data on that gene won't be displayed. This doesn't mean you don't have that gene, just that the genetic test that was performed didn't provide results for that gene, which is why the genetic data file didn't contain any data on that gene.
This can occur because some types of genetic tests, such as those performed by Ancestry.com, 23andMe, MyHeritage and similar companies only test a part of your genome, not your whole genome. Testing your whole genome, which means sequencing all of your genetic data (called 'Whole Genome Sequencing'). Only whole genome sequencing will provide data on all of your genes. If you're interested in Whole Genome Sequencing, this service is provided by several of Sequencing.com's Preferred Provider's of Genetic Testing
Why is there missing data for some genetic variants?
If information appears to be missing from a row then this means the information doesn't exist for that specific variant.
For example, a variant may exist within a gene and therefore the 'Gene' column will be blank. Another variant may not have any known condition associated with it and therefore the 'Condition', 'Interpretation, 'Review Status' and 'References' columns will be blank.
If I see a disease listed, does it mean I'm at risk for that disease?
When the Data Viewer Plus lists a condition (disease, trait, medication reaction, etc.), it doesn't necessarily mean you have a risk for it. Instead, it only means that the specific genetic variant listed in that row has been associated in scientific research with that condition. Whether your genetic data indicates that you are at risk of that ondition will depend upon the interpretation of your raw genetic data. (Your raw genetic data does appear in that table and is listed in the 'Genotype' column.)
For example, if variant rs123 is associated with Cystic Fibros, anytime data contain genetic testing results for rs123, even if the results indicate no-risk, Data Viewer will include rs123 and that it is associated with the condition 'Cystic Fibrosis.' On a technical level, if rs123 has reference allele C and alternative allele T then this means that Cystic Fibrosis risk is likely associated with the "T" allele. If the genetic testing results shown in the 'Genotype' column is 'CC' then there is no risk of Cystic Fibrosis due to variant rs123. But if the Genotype column is 'CT' or 'TT' then there may be a risk of Cystic Fibrosis.
Need assistance understanding your raw genetic data? Use the Genetic Counseling app to speak with a genetic counselor.
Why does my data sometimes reload when I access Data Viewer again?
Sequencing.com's Bioinformatics Team releases updates to Data Viewer on a weekly basis. Some of these updates require the genetic data from your file to 'reload' in your Data Viewer. Reloading of your data in Data Viewer ensures that you always benefit from the most up-to-date version of Data Viewer.
Reloading of data in your Data Viewer is both free and fully automated. It will occur only if there has been an update since the last time you accessed your file's data using your Data Viewer.
Landrum MJ, Lee JM, Benson M, Brown GR, Chao C, Chitipiralla S, Gu B, Hart J, Hoffman D, Jang W, Karapetyan K, Katz K, Liu C, Maddipatla Z, Malheiro A, McDaniel K, Ovetsky M, Riley G, Zhou G, Holmes JB, Kattman BL, Maglott DR. ClinVar: improving access to variant interpretations and supporting evidence. Nucleic Acids Res. 2018 Jan 4. PubMed PMID: 29165669
The genetic analysis and statements that appear in this app have not been evaluated by the United States Food and Drug Administration. The Sequencing.com website and all software applications (Apps) that use Sequencing.com's website, as well as Sequencing.com's open Application Programming Interface (API), are not intended to diagnose, treat, cure, or prevent any disease.