MD · MBA
Physician specializing in genetic analysis and personalized preventive medicine, and author of Outsmart Your Genes.
Brandon Colby is a physician-expert in the fields of genetic analysis and Personalized Preventive Medicine. He holds an MD from the Mount Sinai School of Medicine, an MBA from Stanford University's Graduate School of Business, and a degree in Genetics from the University of Michigan.
Dr. Colby is the author of the book Outsmart Your Genes and has developed numerous technologies that improve the analysis, interpretation, and actionability of genome sequencing data. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics (ACMG), an Associate of the American College of Preventive Medicine (ACPM), and a member of the National Society of Genetic Counselors (NSGC).
Articles by Brandon Colby, MD are reviewed for accuracy by Sequencing's medical and scientific team. This page is for informational purposes and does not constitute medical advice.
Fibro-fatty tissue replaces right ventricular muscle, disrupting electrical conduction and causing palpitations, fainting and sometimes sudden cardiac death.
The left ventricle enlarges and contracts poorly, often silently until heart failure appears; an LMNA mutation that reduces lamin expression is one known cause.
Hereditary syndromes such as BRCA1, BRCA2, Lynch syndrome and Peutz-Jeghers raise risk in some families, and cascade testing lets relatives learn their own status.
Stiffening of the heart muscle stops the heart filling properly; a reported FLNC variant, early onset and relative screening are covered on this page.
Explore how genetic testing enhances diagnosis, early detection, and personalized care for Feingold Syndrome, offering hope and guidance for affected families.
Short stature, distinctive facial features and underdeveloped cartilage point to fibrochondrogenesis, which testing ties to COL11A1 and COL11A2 mutations.
Myoclonic jerks followed by sudden loss of muscle tone cause falls; of 38 children studied for progressive myoclonic epilepsy, 78.9% had an identified mutation.
Craniofacial anomalies and vertebral defects define Goldenhar syndrome, or oculo-auriculo-vertebral spectrum; testing supports diagnosis in atypical cases.