MD · MBA
Physician specializing in genetic analysis and personalized preventive medicine, and author of Outsmart Your Genes.
Brandon Colby is a physician-expert in the fields of genetic analysis and Personalized Preventive Medicine. He holds an MD from the Mount Sinai School of Medicine, an MBA from Stanford University's Graduate School of Business, and a degree in Genetics from the University of Michigan.
Dr. Colby is the author of the book Outsmart Your Genes and has developed numerous technologies that improve the analysis, interpretation, and actionability of genome sequencing data. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics (ACMG), an Associate of the American College of Preventive Medicine (ACPM), and a member of the National Society of Genetic Counselors (NSGC).
Articles by Brandon Colby, MD are reviewed for accuracy by Sequencing's medical and scientific team. This page is for informational purposes and does not constitute medical advice.
Core-like structures inside muscle fibers cause weakness and delayed milestones. Testing NEB, the gene for nebulin, supports diagnosis, care planning and counseling.
Explore how genetic testing detects PTEN mutations, guides cancer screening, supports family planning, and offers hope for managing Cowden Syndrome effectively.
Uneven development of the face and skull can trace back to SF3B2 haploinsufficiency, a finding that shapes early diagnosis, surgical planning and counseling.
Digital clubbing, periostosis and joint pain overlap with other disorders, which is why DNA testing is used here to pin down mutations and shape treatment.
Syndromic forms such as CHARGE can be told apart from isolated suture fusion by finding FGFR2, TWIST1 or CHD7 changes, which also guide the timing of surgery.
Recurrent fevers, urticarial rash and joint pain run through this group of autoinflammatory disorders, and NLRP3 testing can confirm Muckle-Wells syndrome within CAPS.
Loose skin that may involve the lungs, heart and blood vessels can follow dominant, recessive or X-linked inheritance, and PYCR1 is one gene linked to cutis laxa.
Altered CTNS genes stop cystinosin from moving cystine out of lysosomes, damaging the kidneys and eyes; early diagnosis allows cysteamine therapy to begin sooner.