Cold-Induced Sweating Syndrome: Unraveling the Genetic Threads of a Rare Disorder
Heavy sweating in cold conditions, with articulation problems and nasal-sounding speech, marks Cold-Induced Sweating Syndrome, and DNA analysis can confirm it.
Brandon Colby, MD
MD · MBA
Physician specializing in genetic analysis and personalized preventive medicine, and author of Outsmart Your Genes.
About Brandon
Brandon Colby is a physician-expert in the fields of genetic analysis and Personalized Preventive Medicine. He holds an MD from the Mount Sinai School of Medicine, an MBA from Stanford University's Graduate School of Business, and a degree in Genetics from the University of Michigan.
Dr. Colby is the author of the book Outsmart Your Genes and has developed numerous technologies that improve the analysis, interpretation, and actionability of genome sequencing data. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics (ACMG), an Associate of the American College of Preventive Medicine (ACPM), and a member of the National Society of Genetic Counselors (NSGC).
Education
- BA in Genetics with Honors, University of Michigan · 2000
- MD, Mount Sinai School of Medicine · 2004
- MBA, Stanford University Graduate School of Business · 2007
Affiliations & Memberships
- Affiliate Specialist, American College of Medical Genetics and Genomics (ACMG)
- Associate, American College of Preventive Medicine (ACPM)
- Member, National Society of Genetic Counselors (NSGC)
Articles by Brandon Colby, MD are reviewed for accuracy by Sequencing's medical and scientific team. This page is for informational purposes and does not constitute medical advice.
Articles by Brandon
Cracking the Code: Understanding Cole-Carpenter Syndrome Through Genetic Testing
Brittle bones, craniosynostosis and distinctive facial features mark Cole-Carpenter syndrome, and P4HB mutations with endoplasmic reticulum stress help explain them.
Comprehensive Insights into Combined Immunodeficiency: The Role of Genetic Testing
Both humoral and cellular immunity falter, leaving ordinary infections dangerous. Whole-exome sequencing can pinpoint the mutation behind combined immunodeficiency.
Cracking the Code: Genetic Testing and Common Variable Agammaglobulinemia
Low immunoglobulin levels leave people with CVA open to recurrent infection and autoimmune disease, and testing examines genes governing B cell development.
Complex Hereditary Spastic Paraplegia: Unlocking the Genetic Code
Lower-limb spasticity plus peripheral neuropathy, seizures or intellectual disability distinguishes the complex form of HSP, where sequencing can pinpoint the mutation.
Cracking the Code: Genetic Testing for Cone-Rod Dystrophy
Photoreceptor loss in CRD erodes visual acuity, color and peripheral vision; CFAP410 mutations and inheritance patterns guide testing decisions.
Cracking the Code: Understanding Congenital Disorder of Glycosylation through Genetic Testing
Glycosylation attaches sugars to proteins and lipids; when it fails, CDG can bring developmental delay, neurological problems and, in type IIb, hepatosplenomegaly.
Cracking the Code: Understanding Congenital Hydrocephalus Through Genetic Testing
Explore how genetic testing enhances understanding, diagnosis, and personalized treatment of congenital hydrocephalus, improving outcomes and guiding family planning.