MD · MBA
Physician specializing in genetic analysis and personalized preventive medicine, and author of Outsmart Your Genes.
Brandon Colby is a physician-expert in the fields of genetic analysis and Personalized Preventive Medicine. He holds an MD from the Mount Sinai School of Medicine, an MBA from Stanford University's Graduate School of Business, and a degree in Genetics from the University of Michigan.
Dr. Colby is the author of the book Outsmart Your Genes and has developed numerous technologies that improve the analysis, interpretation, and actionability of genome sequencing data. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics (ACMG), an Associate of the American College of Preventive Medicine (ACPM), and a member of the National Society of Genetic Counselors (NSGC).
Articles by Brandon Colby, MD are reviewed for accuracy by Sequencing's medical and scientific team. This page is for informational purposes and does not constitute medical advice.
Discover the role of genetic testing in diagnosing Wieacker-Wolff Syndrome, a rare neuromuscular disorder. Learn about ZC4H2 gene mutations, severity assessment, and management…
Discover the rare genetic condition Woolly Hair, Autosomal Recessive 2, its diagnosis, and the crucial role of genetic testing in understanding and managing this hair disorder.
Intellectual disability, growth failure and epilepsy in males can follow mutations in UBE2A, ATRX, KDM5C or CLCN4; carrier and prenatal testing are described here.
A shortage of catalase lets hydrogen peroxide build up, which can bring oral ulcers and gangrene; many people have no symptoms, and CAT gene sequencing is covered.
Bleeding from a ruptured vessel raises pressure inside the skull and has proved hard to treat; whole genome sequencing is being studied for prognostic biomarkers.
Several foci within one breast quadrant and higher Ki-67 indices set multifocal breast carcinoma apart; whole genome sequencing and immunostaining are explained.
Slow-growing clusters of abnormal veins cause pain, swelling and functional impairment; one study identified ACTA2 as a key contributor to how they form.
Biallelic WDR1 mutations disturb neutrophil function, causing recurrent infections, mild neutropenia, impaired wound healing and severe stomatitis with oral stenosis.