MD · MBA
Physician specializing in genetic analysis and personalized preventive medicine, and author of Outsmart Your Genes.
Brandon Colby is a physician-expert in the fields of genetic analysis and Personalized Preventive Medicine. He holds an MD from the Mount Sinai School of Medicine, an MBA from Stanford University's Graduate School of Business, and a degree in Genetics from the University of Michigan.
Dr. Colby is the author of the book Outsmart Your Genes and has developed numerous technologies that improve the analysis, interpretation, and actionability of genome sequencing data. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics (ACMG), an Associate of the American College of Preventive Medicine (ACPM), and a member of the National Society of Genetic Counselors (NSGC).
Articles by Brandon Colby, MD are reviewed for accuracy by Sequencing's medical and scientific team. This page is for informational purposes and does not constitute medical advice.
An elevated MPV means platelets are larger than normal, a finding linked to cardiovascular disease, diabetes, stroke and variants such as rs7961894.
Osteogenesis imperfecta, caused by mutations in collagen genes, is one reason bones break easily; age, diet and type 2 diabetes also shape fracture risk.
Poor feeding, vomiting, constipation and lethargy can accompany high blood calcium in infants, and mutations in CYP24A1 or SLC34A1 have been linked to the disorder.
Starting in the milk ducts, IDC accounts for about 80% of breast cancers, and BRCA1, BRCA2, hormone receptor, HER2 and Oncotype DX results shape treatment decisions.
A mutation in the insulin receptor gene can reduce receptors at the cell surface, while fasting glucose, oral glucose tolerance and A1C tests measure blood sugar.
Discover the importance of diagnosing Interferon Gamma Receptor Deficiency, its link to other health conditions, and how genetic testing aids in early detection and treatment.
Blood flow to the brain is cut off in ischemic stroke, starving cells of oxygen; the page covers inherited risk, DNA testing and screening of relatives.
Among the inherited contributors to kidney damage are a mutant factor H-related 5 protein and autosomal dominant tubulointerstitial kidney disease.