Decoding Diastolic Dysfunction: Genetic Testing Unravels the Mystery
The left ventricle's failure to fill properly has been linked to Marfan Syndrome with an FBN1 variant, hypertrophic cardiomyopathy and dilated cardiomyopathy.
Brandon Colby, MD
MD · MBA
Physician specializing in genetic analysis and personalized preventive medicine, and author of Outsmart Your Genes.
About Brandon
Brandon Colby is a physician-expert in the fields of genetic analysis and Personalized Preventive Medicine. He holds an MD from the Mount Sinai School of Medicine, an MBA from Stanford University's Graduate School of Business, and a degree in Genetics from the University of Michigan.
Dr. Colby is the author of the book Outsmart Your Genes and has developed numerous technologies that improve the analysis, interpretation, and actionability of genome sequencing data. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics (ACMG), an Associate of the American College of Preventive Medicine (ACPM), and a member of the National Society of Genetic Counselors (NSGC).
Education
- BA in Genetics with Honors, University of Michigan · 2000
- MD, Mount Sinai School of Medicine · 2004
- MBA, Stanford University Graduate School of Business · 2007
Affiliations & Memberships
- Affiliate Specialist, American College of Medical Genetics and Genomics (ACMG)
- Associate, American College of Preventive Medicine (ACPM)
- Member, National Society of Genetic Counselors (NSGC)
Articles by Brandon Colby, MD are reviewed for accuracy by Sequencing's medical and scientific team. This page is for informational purposes and does not constitute medical advice.
Articles by Brandon
Cracking the Genetic Code of Disproportionate Short Stature
Uneven growth between the limbs and trunk has been traced to variants in CCDC53, RAB33B and PCNT and to syndromes such as Noonan, Kabuki and achondroplasia.
Decoding Disseminated Atypical Mycobacterial Infection: Understanding, Diagnosing, and Exploring Genetic Testing
Atypical mycobacteria such as Mycobacterium haemophilum mainly affect immunocompromised people; tissue biopsy, urine culture and PCR help identify the infection.
Ductal Breast Carcinoma Risk Factors and Diagnosis
Beginning in the milk ducts, invasive ductal carcinoma accounts for about 80% of breast cancers, with hormone exposure and reproductive history among its risk factors.
Decoding Dysfibrinogenemia: Understanding, Diagnosing, and Harnessing Genetic Testing
Discover how genetic testing aids in diagnosing dysfibrinogenemia, a rare blood clotting disorder, and its role in guiding treatment, family planning, and genetic counseling.
Adult-Onset Dystonia: TDT Testing and Genetic Risk
Focal symptoms in the neck, hand or face define adult-onset cases; temporal discrimination threshold testing proved more reliable than spatial threshold testing.
Elevated Alkaline Phosphatase: Causes and DNA Testing
Higher ALP in the blood can reflect liver disease, bone disorders or inherited conditions, and blood work plus imaging narrow down what is driving the result.
Empty Follicle Syndrome: Genuine vs False EFS in IVF
No eggs are retrieved despite normal follicles and hormone levels. The page separates genuine from false EFS and covers reported ZP1 and LHCGR mutations.