Decoding Alzheimer Disease 3: Understanding, Diagnosing, and Genetic Testing
An early-onset familial form of Alzheimer's, AD3 is traced to mutations in PSEN1, PSEN2 and APP, with counseling recommended before and after testing.
Brandon Colby, MD
MD · MBA
Physician specializing in genetic analysis and personalized preventive medicine, and author of Outsmart Your Genes.
About Brandon
Brandon Colby is a physician-expert in the fields of genetic analysis and Personalized Preventive Medicine. He holds an MD from the Mount Sinai School of Medicine, an MBA from Stanford University's Graduate School of Business, and a degree in Genetics from the University of Michigan.
Dr. Colby is the author of the book Outsmart Your Genes and has developed numerous technologies that improve the analysis, interpretation, and actionability of genome sequencing data. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics (ACMG), an Associate of the American College of Preventive Medicine (ACPM), and a member of the National Society of Genetic Counselors (NSGC).
Education
- BA in Genetics with Honors, University of Michigan · 2000
- MD, Mount Sinai School of Medicine · 2004
- MBA, Stanford University Graduate School of Business · 2007
Affiliations & Memberships
- Affiliate Specialist, American College of Medical Genetics and Genomics (ACMG)
- Associate, American College of Preventive Medicine (ACPM)
- Member, National Society of Genetic Counselors (NSGC)
Articles by Brandon Colby, MD are reviewed for accuracy by Sequencing's medical and scientific team. This page is for informational purposes and does not constitute medical advice.
Articles by Brandon
Unraveling the Mystery of Analbuminemia: Genetic Testing for Diagnosis and Management
Two mutated copies of the ALB gene leave blood with little or no albumin, bringing edema, fatigue and infections; DNA testing confirms it and finds carriers.
Decoding Anhydramnios: Understanding, Diagnosing, and Using Genetic Testing
Discover the role of genetic testing in diagnosing anhydramnios, understanding its causes, and guiding management strategies to improve pregnancy outcomes.
Scianna Blood Group System: Antigens and DNA Typing
Antigens carried on red blood cells in the Scianna system, tied to the ERMAP gene, affect transfusion compatibility, donor screening and prenatal testing.
Decoding the Enigma of Aortic Root Aneurysm: Understanding, Diagnosing, and Harnessing Genetic Testing
Marfan, Loeys-Dietz and Ehlers-Danlos syndromes are named causes of a widened aortic root, which echocardiography, CT scans and MRI are used to measure.
Unraveling the Asplenia Mystery: Understanding and Diagnosing the Disorder through Genetic Testing
Absence or underdevelopment of the spleen raises infection risk from encapsulated bacteria. Imaging and PKD1L1 gene findings guide diagnosis and prevention.
Autistic Behavior and Genetics: What Research Shows
An unbalanced translocation between chromosomes 10 and 22, plus work on oxytocin and testosterone, frames what genetic testing adds for autistic behavior.
Cracking the Code: Understanding and Diagnosing Autistic Spectrum Disorder with Isolated Skills
Savant abilities appear in roughly 10% of people with ASD. Testing for SNPs and copy number variations can support behavioral assessment and tailored schooling.