GIL Blood Group: Genetic Typing and Transfusion
Serology alone can leave GIL status unclear, so DNA typing is used to confirm the antigen, guide transfusion matching and inform prenatal care planning.
Brandon Colby, MD
MD · MBA
Physician specializing in genetic analysis and personalized preventive medicine, and author of Outsmart Your Genes.
About Brandon
Brandon Colby is a physician-expert in the fields of genetic analysis and Personalized Preventive Medicine. He holds an MD from the Mount Sinai School of Medicine, an MBA from Stanford University's Graduate School of Business, and a degree in Genetics from the University of Michigan.
Dr. Colby is the author of the book Outsmart Your Genes and has developed numerous technologies that improve the analysis, interpretation, and actionability of genome sequencing data. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics (ACMG), an Associate of the American College of Preventive Medicine (ACPM), and a member of the National Society of Genetic Counselors (NSGC).
Education
- BA in Genetics with Honors, University of Michigan · 2000
- MD, Mount Sinai School of Medicine · 2004
- MBA, Stanford University Graduate School of Business · 2007
Affiliations & Memberships
- Affiliate Specialist, American College of Medical Genetics and Genomics (ACMG)
- Associate, American College of Preventive Medicine (ACPM)
- Member, National Society of Genetic Counselors (NSGC)
Articles by Brandon Colby, MD are reviewed for accuracy by Sequencing's medical and scientific team. This page is for informational purposes and does not constitute medical advice.
Articles by Brandon
Glaucoma 1, Open Angle, E: ROCK Gene Polymorphisms
Retinal ganglion cell loss in a transgenic mouse model, ROCK gene polymorphisms in a Korean population and African ancestry are the risk threads set out here.
Glaucoma 1, Open Angle, G: Risk Loci and Obesity
African ancestry, 127 open-angle glaucoma loci and a Mendelian randomization link to obesity shape risk, while Angpt1 knockout mice serve as a research model.
Glipizide Response and TCF7L2 Variation in Type 2 Diabetes
Not everyone with type 2 diabetes responds to glipizide the same way; TCF7L2, GXYLT1 and SLCO1B1 variants have been tied to differences in glycemic response.
Decoding the Mysteries of Greig Cephalopolysyndactyly Syndrome: Genetic Testing for Diagnosis and Treatment
Extra or fused fingers and toes with macrocephaly and a prominent forehead suggest GCPS; GLI3 analysis confirms it and helps anticipate severity.
Unraveling the Complexities of Hemolytic Anemia and Neurological Deficits Due to Glucose Phosphate Isomerase Deficiency
Missing enzyme activity can pair early red cell breakdown with developmental delay and seizures; two patients with novel GPI gene mutations are described in the page.
Demystifying Homocystinuria, cblD Type, Variant 1: The Role of Genetic Testing
MMADHC mutations disturb cobalamin processing, raising methylmalonic acid and homocysteine and bringing developmental delay, seizures and vision problems.
Cracking the Code: Understanding HIV-1 Delayed Disease Progression and the Role of Genetic Testing
Some people carrying HIV-1 reach AIDS far more slowly. Work on nef sequence variation and SDF1 polymorphism, tailored therapy and drug-resistance tracking is set out.