Decoding the Genetic Mysteries of Atopy Susceptibility
Variants in NF-κB and TIM-1 shape who develops asthma, eczema or hay fever; skin prick tests, blood tests and gene analysis are used to assess atopy susceptibility.
Brandon Colby, MD
MD · MBA
Physician specializing in genetic analysis and personalized preventive medicine, and author of Outsmart Your Genes.
About Brandon
Brandon Colby is a physician-expert in the fields of genetic analysis and Personalized Preventive Medicine. He holds an MD from the Mount Sinai School of Medicine, an MBA from Stanford University's Graduate School of Business, and a degree in Genetics from the University of Michigan.
Dr. Colby is the author of the book Outsmart Your Genes and has developed numerous technologies that improve the analysis, interpretation, and actionability of genome sequencing data. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics (ACMG), an Associate of the American College of Preventive Medicine (ACPM), and a member of the National Society of Genetic Counselors (NSGC).
Education
- BA in Genetics with Honors, University of Michigan · 2000
- MD, Mount Sinai School of Medicine · 2004
- MBA, Stanford University Graduate School of Business · 2007
Affiliations & Memberships
- Affiliate Specialist, American College of Medical Genetics and Genomics (ACMG)
- Associate, American College of Preventive Medicine (ACPM)
- Member, National Society of Genetic Counselors (NSGC)
Articles by Brandon Colby, MD are reviewed for accuracy by Sequencing's medical and scientific team. This page is for informational purposes and does not constitute medical advice.
Articles by Brandon
AVSD vs ASD and VSD: What Genetic Testing Shows
Poor weight gain, breathlessness and repeated chest infections point to atrioventricular septal defect; gene testing separates it from ASD and VSD in unclear cases.
Bartter Syndrome Type 3 with Hypocalciuria: CLCNKB
Loss-of-function CLCNKB variants track with earlier diagnosis and higher chronic kidney disease risk, alongside lab findings and cases recognised in elderly patients.
Bilateral Microphthalmos and Its Genetic Causes
Eyes that are much smaller than usual at birth can mean vision loss or blindness. Next-generation sequencing is described as a way to find the variants involved.
Blood Group Froese: ABO Gene Deletion and Testing
A 24-base pair deletion in the ABO gene causes a hereditary splice site defect tied to this rare group. DNA testing from blood or saliva can detect it.
BMIQTL4: Genetic Testing and BMI Regulation
Linkage analysis across 1,812 families found genetic heterogeneity behind BMI, and the page sets BMIQTL4 beside BDNF rs6265 findings and AutoQTL methods.
Deciphering the Mysteries of Campomelic Dysplasia with Autosomal Sex Reversal
Discover the role of genetic testing in diagnosing Campomelic Dysplasia with Autosomal Sex Reversal, guiding treatment, and supporting research for this rare genetic disorder.
Carotid Intimal Medial Thickness: How CIMT Is Measured
Ultrasound of the carotid arteries measures wall thickness, an early atherosclerosis marker. CIMT in type 2 diabetes, β-thalassemia major and lupus is reviewed.