MD · MBA
Physician specializing in genetic analysis and personalized preventive medicine, and author of Outsmart Your Genes.
Brandon Colby is a physician-expert in the fields of genetic analysis and Personalized Preventive Medicine. He holds an MD from the Mount Sinai School of Medicine, an MBA from Stanford University's Graduate School of Business, and a degree in Genetics from the University of Michigan.
Dr. Colby is the author of the book Outsmart Your Genes and has developed numerous technologies that improve the analysis, interpretation, and actionability of genome sequencing data. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics (ACMG), an Associate of the American College of Preventive Medicine (ACPM), and a member of the National Society of Genetic Counselors (NSGC).
Articles by Brandon Colby, MD are reviewed for accuracy by Sequencing's medical and scientific team. This page is for informational purposes and does not constitute medical advice.
Discover the causes, diagnosis, and benefits of genetic testing for NOR Polyagglutination Syndrome, a rare blood disorder affecting red blood cells and overall health.
Clouding of the lens nucleus from birth or early childhood defines this congenital cataract. Reported CRYBB1 and GJA3 mutations and carrier screening are set out.
Underdevelopment of the cerebellum, pons and olivary nuclei in OPCH affects balance and motor skills; MRI with CASK, TSEN54, RARS2 and VRK1 testing aids diagnosis.
Seizures, developmental delay and hormonal imbalance can accompany underdeveloped optic nerves; whole exome sequencing can identify FOXA2 mutations.
Low bone mass before age 50 can trace to mutations such as a heterozygous WNT1 variant, and diet, exercise and carbonated drinks are covered alongside genetic testing.
Serological typing can miss this rare blood group, in which FUT1 mutations reduce ABO antigens on red cells and raise risks during transfusion and transplantation.
Cold or exertion can trigger muscle stiffness, while high blood potassium accompanies bouts of weakness; both conditions stem from mutations in the SCN4A gene.
Developmental delay, hearing loss, vision problems and liver dysfunction follow faulty peroxisomes; PBD3B sits in the Zellweger spectrum and PEX6 variants are reported.