MD · MBA
Physician specializing in genetic analysis and personalized preventive medicine, and author of Outsmart Your Genes.
Brandon Colby is a physician-expert in the fields of genetic analysis and Personalized Preventive Medicine. He holds an MD from the Mount Sinai School of Medicine, an MBA from Stanford University's Graduate School of Business, and a degree in Genetics from the University of Michigan.
Dr. Colby is the author of the book Outsmart Your Genes and has developed numerous technologies that improve the analysis, interpretation, and actionability of genome sequencing data. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics (ACMG), an Associate of the American College of Preventive Medicine (ACPM), and a member of the National Society of Genetic Counselors (NSGC).
Articles by Brandon Colby, MD are reviewed for accuracy by Sequencing's medical and scientific team. This page is for informational purposes and does not constitute medical advice.
Alpha-1-antitrypsin shields the lungs from damaging enzymes. SERPINA1 mutations reduce it, raising the risk of emphysema and liver disease. Blood and DNA tests confirm.
Low or faulty von Willebrand factor causes excessive bleeding. Genetic testing separates subtypes such as Type 2M Milwaukee-1 and vWD Sungnam.
Red cells with no Rh antigens can show stomatocytosis and increased osmotic fragility. Blood typing, molecular analysis, carriers and transfusion care are described.
Discover the importance of genetic testing for RhD negative blood in blood donor screening, prenatal testing, personalized medicine, and population genetics. Learn about diagnosis…
Rod and cone photoreceptors lose function progressively, bringing night blindness and reduced acuity. ERG, OCT and gene testing are compared, with their limits.
Understand SHBG Deficiency, its diagnosis, and the importance of genetic testing for hormonal imbalances. Learn about personalized treatment strategies.
Discover the mysteries of Familial Natural Short Sleep, its genetic basis, and how genetic testing can help diagnose this rare sleep condition for a healthier lifestyle.
Some people function well on four to six hours of sleep, a trait tied to the dec2P384R mutation and to DEC2, NPSR1, mGluR1 and B1-AR variants in FNSS.