Decoding the Enigma of Abnormal Glucose-6-Phosphate Dehydrogenase Concentration: A Comprehensive Guide
Low G6PD activity can cause neonatal jaundice and hemolytic anemia; enzyme measurement, Heinz body checks and genotyping identify the variant.
Brandon Colby, MD
MD · MBA
Physician specializing in genetic analysis and personalized preventive medicine, and author of Outsmart Your Genes.
About Brandon
Brandon Colby is a physician-expert in the fields of genetic analysis and Personalized Preventive Medicine. He holds an MD from the Mount Sinai School of Medicine, an MBA from Stanford University's Graduate School of Business, and a degree in Genetics from the University of Michigan.
Dr. Colby is the author of the book Outsmart Your Genes and has developed numerous technologies that improve the analysis, interpretation, and actionability of genome sequencing data. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics (ACMG), an Associate of the American College of Preventive Medicine (ACPM), and a member of the National Society of Genetic Counselors (NSGC).
Education
- BA in Genetics with Honors, University of Michigan · 2000
- MD, Mount Sinai School of Medicine · 2004
- MBA, Stanford University Graduate School of Business · 2007
Affiliations & Memberships
- Affiliate Specialist, American College of Medical Genetics and Genomics (ACMG)
- Associate, American College of Preventive Medicine (ACPM)
- Member, National Society of Genetic Counselors (NSGC)
Articles by Brandon Colby, MD are reviewed for accuracy by Sequencing's medical and scientific team. This page is for informational purposes and does not constitute medical advice.
Articles by Brandon
Decoding Dyslipidemia: Understanding, Diagnosing, and Using Genetic Testing for Abnormal Circulating Lipid Concentrations
Abdominal adiposity, the gut microbiome and inherited lipid species all shape circulating lipid levels, with SPTLC3 named as a possible target.
Understanding, Diagnosing, and Using Genetic Testing for Abnormal Circulating Porphyrin Concentration
Porphyrins help build hemoglobin and cytochrome, so abnormal blood levels can mean anemia, photosensitivity or an enzyme deficiency behind porphyria.
Decoding the Enigma of Abnormal Circulating Thyroid Hormone Concentration
Blood tests for T3, T4 and TSH open the work-up, and gene testing, for instance for MCT8 deficiency, can show why hormone levels sit outside the range.
Decoding Abnormal Intrahepatic Bile Duct Morphology: A Comprehensive Guide
Malformed bile ducts inside the liver sit behind biliary atresia, duct stones and sclerosing cholangitis, imaged by ultrasound, MRCP and ERCP.
Unlocking the Mystery of Abnormal Lactate Dehydrogenase Levels: A Guide to Understanding, Diagnosing, and Genetic Testing
Discover the importance of lactate dehydrogenase (LDH) in diagnosing health issues, and learn how genetic testing can help identify underlying causes and optimize treatment plans.
Decoding Abnormal Mitral Valve Physiology: Genetic Testing Unlocks New Insights
Prolapse, regurgitation or stenosis of the mitral valve can cause breathlessness, fatigue and chest pain, with echocardiography the main assessment.
Abnormal Radial Ray Morphology and Genetic Testing
Malformations of the thumb, radius and preaxial carpal bones range from mild thumb hypoplasia to severe limb defects, and DNA testing can find the cause.