MD · MBA
Physician specializing in genetic analysis and personalized preventive medicine, and author of Outsmart Your Genes.
Brandon Colby is a physician-expert in the fields of genetic analysis and Personalized Preventive Medicine. He holds an MD from the Mount Sinai School of Medicine, an MBA from Stanford University's Graduate School of Business, and a degree in Genetics from the University of Michigan.
Dr. Colby is the author of the book Outsmart Your Genes and has developed numerous technologies that improve the analysis, interpretation, and actionability of genome sequencing data. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics (ACMG), an Associate of the American College of Preventive Medicine (ACPM), and a member of the National Society of Genetic Counselors (NSGC).
Articles by Brandon Colby, MD are reviewed for accuracy by Sequencing's medical and scientific team. This page is for informational purposes and does not constitute medical advice.
Reduced gonadal function with elevated gonadotropins can bring delayed puberty, primary amenorrhea and infertility. SOHLH1 and INHA findings and testing are covered.
Middle ear inflammation with fluid buildup and temporary hearing loss has genetic contributors, including an A2ML1 variant and Galnt2 and Nischarin mouse findings.
Because this rare form is inherited in an autosomal dominant pattern, an affected person has a 50% chance of passing it on. Diagnosis and testing uses are outlined.
Discover the causes of Dominant Optic Atrophy (DOA), its diagnosis, and the importance of genetic testing for early detection, carrier identification, and prenatal planning.
Autosomal recessive inheritance means two copies of the mutated gene; recessive optic atrophy brings declining acuity, color vision deficits and visual field loss.
Most Parkinson's disease is sporadic, but this rare inherited form is confirmed with genetic testing alongside clinical symptoms, medical history and imaging studies.
Ethnicity, gene mutations and predictive biomarkers shape how patients respond to pazopanib, a tyrosine kinase inhibitor used in renal cell carcinoma and sarcoma.
Nodules of misplaced nerve cells appear alongside webbed digits and a cleft palate; FLNA, ARFGEF2, PQBP1 and NEDD4L are among the genes reported in this disorder.