Understanding Short QT Syndrome: Diagnosing and Using Genetic Testing
A QT interval under 330 milliseconds on an ECG can signal short QT syndrome, an autosomal dominant condition linked to KCNH2, KCNQ1 and KCNJ2 variants.
Brandon Colby, MD
MD · MBA
Physician specializing in genetic analysis and personalized preventive medicine, and author of Outsmart Your Genes.
About Brandon
Brandon Colby is a physician-expert in the fields of genetic analysis and Personalized Preventive Medicine. He holds an MD from the Mount Sinai School of Medicine, an MBA from Stanford University's Graduate School of Business, and a degree in Genetics from the University of Michigan.
Dr. Colby is the author of the book Outsmart Your Genes and has developed numerous technologies that improve the analysis, interpretation, and actionability of genome sequencing data. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics (ACMG), an Associate of the American College of Preventive Medicine (ACPM), and a member of the National Society of Genetic Counselors (NSGC).
Education
- BA in Genetics with Honors, University of Michigan · 2000
- MD, Mount Sinai School of Medicine · 2004
- MBA, Stanford University Graduate School of Business · 2007
Affiliations & Memberships
- Affiliate Specialist, American College of Medical Genetics and Genomics (ACMG)
- Associate, American College of Preventive Medicine (ACPM)
- Member, National Society of Genetic Counselors (NSGC)
Articles by Brandon Colby, MD are reviewed for accuracy by Sequencing's medical and scientific team. This page is for informational purposes and does not constitute medical advice.
Articles by Brandon
Understanding, Diagnosing, and Using Genetic Testing for Sigmoid Colon Cancer
Changes in bowel habits, blood in the stool and weight loss can signal cancer of the sigmoid colon; colonoscopy confirms it and APC, KRAS or TP53 testing guides care.
Understanding, Diagnosing, and Using Genetic Testing for Sleep-related Hypermotor Epilepsy
Thrashing or kicking episodes during sleep can be mistaken for night terrors; video-EEG, polysomnography and CHRNA4, CHRNB2 and KCNT1 testing help confirm SHE.
Understanding, Diagnosing, and Using Genetic Testing for Small Vessel Cerebrovascular Disease
Discover the causes, diagnosis, and the role of genetic testing in managing small vessel cerebrovascular disease. Learn about symptoms, imaging, and personalized treatments.
Understanding, Diagnosing, and Using Genetic Testing for Spastic Cerebral Palsy
Stiff, jerky movements follow damage to the developing brain; medical history, physical examination and MRI or CT imaging lead to a diagnosis of spastic cerebral palsy.
Understanding, Diagnosing, and Using Genetic Testing for Spinal Muscular Atrophy
Loss of motor neurons in the spinal cord and brainstem weakens muscles; a blood test for SMN1 mutations confirms SMA and supports carrier, prenatal and newborn screening.
Understanding Spinocerebellar Atrophy: Diagnosis and Genetic Testing
Diagnosing Spinocerebellar Atrophy: Understand symptoms, clinical exams, and how genetic testing plays a crucial role in managing this hereditary neurological disorder.
Understanding, Diagnosing, and Using Genetic Testing for Spondylocostal Dysostosis
Malformed vertebrae and ribs can restrict lung growth and cause scoliosis in spondylocostal dysostosis; DLL3, MESP2, LFNG and HES7 are among the genes tested.