MD · MBA
Physician specializing in genetic analysis and personalized preventive medicine, and author of Outsmart Your Genes.
Brandon Colby is a physician-expert in the fields of genetic analysis and Personalized Preventive Medicine. He holds an MD from the Mount Sinai School of Medicine, an MBA from Stanford University's Graduate School of Business, and a degree in Genetics from the University of Michigan.
Dr. Colby is the author of the book Outsmart Your Genes and has developed numerous technologies that improve the analysis, interpretation, and actionability of genome sequencing data. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics (ACMG), an Associate of the American College of Preventive Medicine (ACPM), and a member of the National Society of Genetic Counselors (NSGC).
Articles by Brandon Colby, MD are reviewed for accuracy by Sequencing's medical and scientific team. This page is for informational purposes and does not constitute medical advice.
Discover the role of genetic testing in diagnosing early-onset Alzheimer's, understand its symptoms, and explore the ethical considerations of genetic testing.
Surfactant protein gene changes can leave a child with persistent cough, rapid breathing and failure to thrive; CT, lung function tests and DNA testing follow.
Drooping eyelids and limited eye movement come from mtDNA deletions that starve muscle of energy; EMG, muscle biopsy, blood tests and DNA analysis confirm PEO.
Surfactant builds up in the alveoli, bringing breathlessness, cough and fatigue; autoimmune, secondary and congenital forms differ, and SFTPB or ABCA3 testing helps.
Protein C normally switches off clotting factors Va and VIIIa. When its activity falls, through inherited PROC variants or liver disease, venous clotting risk rises.
Visual field testing, ERG and OCT can point to RP43, while targeted gene sequencing or whole exome sequencing identifies the mutation and opens trial eligibility.
Visual field testing, electroretinography and OCT point toward RP6, and a DNA result confirms the mutation and identifies carriers within a family.
Explore scapuloperoneal myopathy, its symptoms, diagnosis using EMG, muscle biopsy, and the crucial role of genetic testing for accurate identification and family planning.