Understanding, Diagnosing, and Using Genetic Testing for Dentin Dysplasia Type I
Short blunt roots, obliterated pulp chambers and premature tooth loss point to dentin dysplasia type I, an autosomal dominant disorder that DNA testing can confirm.
Brandon Colby, MD
MD · MBA
Physician specializing in genetic analysis and personalized preventive medicine, and author of Outsmart Your Genes.
About Brandon
Brandon Colby is a physician-expert in the fields of genetic analysis and Personalized Preventive Medicine. He holds an MD from the Mount Sinai School of Medicine, an MBA from Stanford University's Graduate School of Business, and a degree in Genetics from the University of Michigan.
Dr. Colby is the author of the book Outsmart Your Genes and has developed numerous technologies that improve the analysis, interpretation, and actionability of genome sequencing data. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics (ACMG), an Associate of the American College of Preventive Medicine (ACPM), and a member of the National Society of Genetic Counselors (NSGC).
Education
- BA in Genetics with Honors, University of Michigan · 2000
- MD, Mount Sinai School of Medicine · 2004
- MBA, Stanford University Graduate School of Business · 2007
Affiliations & Memberships
- Affiliate Specialist, American College of Medical Genetics and Genomics (ACMG)
- Associate, American College of Preventive Medicine (ACPM)
- Member, National Society of Genetic Counselors (NSGC)
Articles by Brandon Colby, MD are reviewed for accuracy by Sequencing's medical and scientific team. This page is for informational purposes and does not constitute medical advice.
Articles by Brandon
Understanding, Diagnosing, and Using Genetic Testing for Dentinogenesis Imperfecta Type 2
Opalescent, brownish-blue or amber teeth and obliterated pulp chambers on X-ray point to DI2, an autosomal dominant dentin disorder that DSPP testing can confirm.
Understanding, Diagnosing, and Using Genetic Testing for Dentinogenesis Imperfecta Type 3
Understanding Dentinogenesis Imperfecta Type 3: symptoms, diagnosis through clinical evaluation, radiographic imaging, and genetic testing for personalized treatment and family…
Understanding Dermatopathia Pigmentosa Reticularis: Diagnosis and the Role of Genetic Testing
A net-like pattern of skin pigmentation, non-scarring alopecia and nail dystrophy define DPR, an autosomal dominant ectodermal dysplasia caused by KRT14 mutations.
Understanding, Diagnosing, and Using Genetic Testing for Nephrogenic Diabetes Insipidus
Kidneys that cannot respond to antidiuretic hormone cause the polyuria and dehydration of nephrogenic diabetes insipidus, confirmed by AQP2 or AVPR2 testing.
Understanding, Diagnosing, and Using Genetic Testing for Diaphyseal Medullary Stenosis-Bone Malignancy Syndrome
Progressive narrowing of the marrow cavity in long bones raises osteosarcoma risk in DMS-BMS; EIF2AK3 testing confirms it and flags relatives for surveillance.
Understanding, Diagnosing, and Using Genetic Testing for Diastema
A gap between the front teeth may come from tooth size, jaw structure or habits such as thumb-sucking, and is assessed with a dental exam, X-rays and genetic testing.
Understanding, Diagnosing, and Using Genetic Testing for Dilated Cardiomyopathy 1A
Shortness of breath, fatigue, leg swelling and irregular heartbeats point to DCM1A, which is assessed with echocardiography, ECG, cardiac MRI and genetic testing.