Illuminating Isolated Hyperchlorhidrosis: The Role of Genetic Testing
Sweating far beyond need on palms, soles and underarms with no clear cause defines isolated hyperchlorhidrosis; testing looks for markers and family patterns.
Brandon Colby, MD
MD · MBA
Physician specializing in genetic analysis and personalized preventive medicine, and author of Outsmart Your Genes.
About Brandon
Brandon Colby is a physician-expert in the fields of genetic analysis and Personalized Preventive Medicine. He holds an MD from the Mount Sinai School of Medicine, an MBA from Stanford University's Graduate School of Business, and a degree in Genetics from the University of Michigan.
Dr. Colby is the author of the book Outsmart Your Genes and has developed numerous technologies that improve the analysis, interpretation, and actionability of genome sequencing data. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics (ACMG), an Associate of the American College of Preventive Medicine (ACPM), and a member of the National Society of Genetic Counselors (NSGC).
Education
- BA in Genetics with Honors, University of Michigan · 2000
- MD, Mount Sinai School of Medicine · 2004
- MBA, Stanford University Graduate School of Business · 2007
Affiliations & Memberships
- Affiliate Specialist, American College of Medical Genetics and Genomics (ACMG)
- Associate, American College of Preventive Medicine (ACPM)
- Member, National Society of Genetic Counselors (NSGC)
Articles by Brandon Colby, MD are reviewed for accuracy by Sequencing's medical and scientific team. This page is for informational purposes and does not constitute medical advice.
Articles by Brandon
Linking Genetics with Lateral Meningocele Syndrome: Unlocking the Code
Protrusions of the meninges through the vertebrae come with skeletal and sometimes neurological problems; a mouse study of bone density is summarized.
Mapping Malignant Hyperthermia: Understanding Susceptibility Through Genetic Testing
Calcium escapes inside muscle cells when RYR1, or less often CACNA1S, carries a mutation; knowing your status lets anesthesiologists avoid triggering agents.
Esophageal Melanoma: Tumor Mutations and Testing
Melanocytes in the esophageal lining can turn cancerous in this rare, aggressive tumor; profiling of 15 tumors points toward targeted treatment.
Mysteries of Mucosa-Associated Lymphoma: Unlocking the Genetic Code
About 10% of gastric cases occur without Helicobacter pylori, and the t(11;18) API2-MALT1 fusion can guide treatment and monitoring in MALT lymphoma.
Mastering Multiple Endocrine Neoplasia, Type 1: The Promise of Genetic Testing
Tumor risk in three endocrine sites traces to the MEN1 gene, which is passed on in an autosomal dominant pattern with a 50% chance for each child.
Mapping the Mysteries of Multiple Epiphyseal Dysplasia Type 1: The Role of Genetic Testing
Delayed, irregular ossification of the epiphyses leads to joint pain, stiffness and early osteoarthritis; COMP mutations distinguish MED1 from similar disorders.
Mapping the Mysteries of Multiple Fibrofolliculomas: Genetic Testing's Role in Diagnosis and Management
Skin tumors that are the hallmark of Birt–Hogg–Dubé syndrome come alongside renal tumors and pulmonary cysts; FLCN testing guides surveillance and family risk.