MD · MBA
Physician specializing in genetic analysis and personalized preventive medicine, and author of Outsmart Your Genes.
Brandon Colby is a physician-expert in the fields of genetic analysis and Personalized Preventive Medicine. He holds an MD from the Mount Sinai School of Medicine, an MBA from Stanford University's Graduate School of Business, and a degree in Genetics from the University of Michigan.
Dr. Colby is the author of the book Outsmart Your Genes and has developed numerous technologies that improve the analysis, interpretation, and actionability of genome sequencing data. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics (ACMG), an Associate of the American College of Preventive Medicine (ACPM), and a member of the National Society of Genetic Counselors (NSGC).
Articles by Brandon Colby, MD are reviewed for accuracy by Sequencing's medical and scientific team. This page is for informational purposes and does not constitute medical advice.
Rapid neurological decline with blindness, loss of coordination and muscle stiffness begins in childhood; DNA analysis helps separate it from similar disorders.
Gain insights into Ehlers-Danlos syndrome musculocontractural type 2 and understand how genetic testing aids in diagnosis, treatment strategies, and family planning.
Variants in SCN11A, SCN10A and SCN9A alter how sodium channels carry pain signals, producing the recurring pain attacks that define FEPS and guiding testing.
Sudden bouts of intense pain in the lower limbs run in families; genetic testing can confirm the diagnosis, separate it from similar conditions and shape pain management.
Irregular periods, infertility and galactorrhea can follow from too much prolactin, and inherited mutations distinguish the familial form from drug-related causes.
Truncated apolipoprotein B leaves LDL very low in FHBL1 and can bring fat malabsorption and liver disease; the autosomal dominant pattern means a 50% chance per child.
Glucose, amino acids, phosphate and bicarbonate are lost in the urine here, which can bring growth retardation, bone deformities and maturity-onset diabetes.
Mitochondrial gene mutations disturb energy production in this growth and developmental delay syndrome; early molecular diagnosis shapes care and counseling.