Tenorio Syndrome: Unlocking the Genetic Code to Better Understand and Manage the Condition
Distinctive facial features, developmental delays and other physical anomalies mark Tenorio syndrome, a rare disorder that genetic testing can confirm.
Brandon Colby, MD
MD · MBA
Physician specializing in genetic analysis and personalized preventive medicine, and author of Outsmart Your Genes.
About Brandon
Brandon Colby is a physician-expert in the fields of genetic analysis and Personalized Preventive Medicine. He holds an MD from the Mount Sinai School of Medicine, an MBA from Stanford University's Graduate School of Business, and a degree in Genetics from the University of Michigan.
Dr. Colby is the author of the book Outsmart Your Genes and has developed numerous technologies that improve the analysis, interpretation, and actionability of genome sequencing data. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics (ACMG), an Associate of the American College of Preventive Medicine (ACPM), and a member of the National Society of Genetic Counselors (NSGC).
Education
- BA in Genetics with Honors, University of Michigan · 2000
- MD, Mount Sinai School of Medicine · 2004
- MBA, Stanford University Graduate School of Business · 2007
Affiliations & Memberships
- Affiliate Specialist, American College of Medical Genetics and Genomics (ACMG)
- Associate, American College of Preventive Medicine (ACPM)
- Member, National Society of Genetic Counselors (NSGC)
Articles by Brandon Colby, MD are reviewed for accuracy by Sequencing's medical and scientific team. This page is for informational purposes and does not constitute medical advice.
Articles by Brandon
Thyroid Cancer, Nonmedullary, 4: TPO Gene Mutations
Mutations in the thyroid peroxidase (TPO) gene can destabilize the protein. NMTC4 testing is presented as a route to earlier diagnosis and targeted therapy.
Thyroid Cancer, Nonmedullary, 5: A Hereditary Subtype
Families affected by this inherited thyroid cancer are pointed toward thyroid peroxidase mutation testing for risk assessment and treatment planning.
Teeth in Transition: Understanding Tooth Agenesis, Selective, 7 through Genetic Testing
WNT10A and EDA guide dental tissue development, and mutations there cause syndromic or isolated missing teeth. Early testing aids orthodontic and prosthetic planning.
Tracing Trichothiodystrophy 2, Photosensitive: The Role of Genetic Testing in Early Diagnosis
Faults in ERCC2/XPD leave the body unable to repair UV-induced DNA damage, producing brittle hair and sun sensitivity. Early detection and cost barriers are discussed.
Tracing the Threads of Trichothiodystrophy 3, Photosensitive: Unraveling the Role of Genetic Testing
Brittle hair, developmental delay and raised sensitivity to ultraviolet light appear in TTD3. Facial-feature research and testing for earlier diagnosis are covered.
Unraveling Ullrich Congenital Muscular Dystrophy 2: The Role of Genetic Testing
A homozygous splice site variant in COL6A1, found in a consanguineous Malian family, ties UCMD2 to the muscle weakness and joint problems seen in infancy.
Zeroing in on Zimmermann-Laband Syndrome 2: The Role of Genetic Testing
Gum overgrowth, nail dysplasia and facial anomalies point to ZLS2, a rare disorder where DNA analysis confirms the diagnosis and informs family planning.