MD · MBA
Physician specializing in genetic analysis and personalized preventive medicine, and author of Outsmart Your Genes.
Brandon Colby is a physician-expert in the fields of genetic analysis and Personalized Preventive Medicine. He holds an MD from the Mount Sinai School of Medicine, an MBA from Stanford University's Graduate School of Business, and a degree in Genetics from the University of Michigan.
Dr. Colby is the author of the book Outsmart Your Genes and has developed numerous technologies that improve the analysis, interpretation, and actionability of genome sequencing data. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics (ACMG), an Associate of the American College of Preventive Medicine (ACPM), and a member of the National Society of Genetic Counselors (NSGC).
Articles by Brandon Colby, MD are reviewed for accuracy by Sequencing's medical and scientific team. This page is for informational purposes and does not constitute medical advice.
Named after Dr. Hilde Van Esch, XLID-VE causes intellectual disability and developmental delays mainly in males; carrier testing and counseling are covered here.
Extreme sun sensitivity, neurological abnormalities and growth deficiency combine in XP/CS, a disorder of the nucleotide excision repair pathway that testing can confirm.
Amyloid-beta peptides collecting in the brain and its blood vessels bring cerebral hemorrhage and cognitive decline; APP gene testing identifies the mutation.
Deletions in mitochondrial DNA tied to DGUOK deficiency can bring muscle weakness, neurological problems and liver dysfunction that only appear later in life.
Uncover how genetic testing aids in diagnosing rare Alazami-Yuan syndrome, guiding personalized treatments and empowering families with valuable insights.
Unusually soft enamel raises sensitivity and discoloration in this subtype, and DNA analysis distinguishes IIa6 from other forms of amelogenesis imperfecta.
Hypoplastic and hypomineralized enamel traces back to AMELX, the gene for amelogenin; a newly reported variant shows what sequencing can add to dental care.
A frameshift mutation in the RELT gene disrupts enamel formation, leaving teeth thin, soft and prone to cavities. Genetic testing supports early dental care.