Warburg Micro Syndrome: Unveiling the Genetic Puzzle
Microcephaly, intellectual disability and distinctive facial features follow mutations in genes such as RAB3GAP1, with osteopenia reported as a further feature.
Brandon Colby, MD
MD · MBA
Physician specializing in genetic analysis and personalized preventive medicine, and author of Outsmart Your Genes.
About Brandon
Brandon Colby is a physician-expert in the fields of genetic analysis and Personalized Preventive Medicine. He holds an MD from the Mount Sinai School of Medicine, an MBA from Stanford University's Graduate School of Business, and a degree in Genetics from the University of Michigan.
Dr. Colby is the author of the book Outsmart Your Genes and has developed numerous technologies that improve the analysis, interpretation, and actionability of genome sequencing data. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics (ACMG), an Associate of the American College of Preventive Medicine (ACPM), and a member of the National Society of Genetic Counselors (NSGC).
Education
- BA in Genetics with Honors, University of Michigan · 2000
- MD, Mount Sinai School of Medicine · 2004
- MBA, Stanford University Graduate School of Business · 2007
Affiliations & Memberships
- Affiliate Specialist, American College of Medical Genetics and Genomics (ACMG)
- Associate, American College of Preventive Medicine (ACPM)
- Member, National Society of Genetic Counselors (NSGC)
Articles by Brandon Colby, MD are reviewed for accuracy by Sequencing's medical and scientific team. This page is for informational purposes and does not constitute medical advice.
Articles by Brandon
Young-onset Parkinson Disease: Decoding the Genetic Puzzle
Mutations in LRRK2, PRKN, PINK1 and DJ-1 are linked to Parkinson disease starting before age 50, and testing helps separate YOPD from other movement disorders.
Genetic Testing for Thyroid Tumors: What It Can Show
Variants in BRAF, RET and RAS help predict how a thyroid tumor behaves and whether targeted therapy fits, with notes on family risk and carotid body tumor cases.
Decoding 2-Hydroxyglutaric Aciduria: The Role of Genetic Testing
Excess 2-hydroxyglutaric acid in urine can bring developmental delays, seizures and muscle hypotonia; testing separates Type I (L2HGDH) from Type II (IDH2).
Genes Behind Abnormal Pulmonary Interstitial Morphology
Scarring in the tissue around the air sacs stiffens the lungs, and telomere- and surfactant-related mutations are recognised in pulmonary fibrosis.
Agammaglobulinemia: Unraveling the Genetic Threads of a Complex Immune Disorder
Without gamma globulins the body cannot fight bacterial infections. X-linked agammaglobulinemia is the most common form, and DNA testing can identify the mutation.
Unlocking the Mysteries of Alternating Hemiplegia of Childhood: The Role of Genetic Testing
Episodes of paralysis that switch from one side of the body to the other begin before 18 months in AHC, and ATP1A3 analysis can confirm the diagnosis.
Addressing Aplastic Anemia: Genetic Testing as a Guiding Light
When bone marrow stops making enough blood cells, fatigue, infections and bleeding follow, and inherited causes such as Fanconi anemia can be found by DNA testing.