Fasting Plasma Glucose QTL 5: Insulin and Glucose Studies
Linkage of fasting insulin to chromosome 17 and mouse work naming tomosyn-2 as a negative regulator of insulin secretion sit behind this locus and its research.
Brandon Colby, MD
MD · MBA
Physician specializing in genetic analysis and personalized preventive medicine, and author of Outsmart Your Genes.
About Brandon
Brandon Colby is a physician-expert in the fields of genetic analysis and Personalized Preventive Medicine. He holds an MD from the Mount Sinai School of Medicine, an MBA from Stanford University's Graduate School of Business, and a degree in Genetics from the University of Michigan.
Dr. Colby is the author of the book Outsmart Your Genes and has developed numerous technologies that improve the analysis, interpretation, and actionability of genome sequencing data. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics (ACMG), an Associate of the American College of Preventive Medicine (ACPM), and a member of the National Society of Genetic Counselors (NSGC).
Education
- BA in Genetics with Honors, University of Michigan · 2000
- MD, Mount Sinai School of Medicine · 2004
- MBA, Stanford University Graduate School of Business · 2007
Affiliations & Memberships
- Affiliate Specialist, American College of Medical Genetics and Genomics (ACMG)
- Associate, American College of Preventive Medicine (ACPM)
- Member, National Society of Genetic Counselors (NSGC)
Articles by Brandon Colby, MD are reviewed for accuracy by Sequencing's medical and scientific team. This page is for informational purposes and does not constitute medical advice.
Articles by Brandon
QTL6 on Chromosome 6q23: HbF and Sickle Cell Disease
Higher fetal hemoglobin is tied to milder sickle cell symptoms, and QTL6 on chromosome 6q23 helps explain why, supporting early diagnosis and treatment planning.
Decoding the Mystery: Understanding and Diagnosing TARDBP-Related Frontotemporal Dementia
Abnormal TDP-43 protein clumps in the brain mark this subtype of frontotemporal dementia; finding a TARDBP mutation confirms it and flags at-risk relatives.
Glaucoma 1, Open Angle, P: ANGPT2 and TNF-α Links
Blocked drainage canals raise eye pressure in POAG; an ANGPT2 SNP was tied to normal tension glaucoma in Shantou males, and TNF-308*AA to disease risk.
Understanding and Tackling GLUT1 Deficiency Syndrome 1: The Power of Genetic Testing
Both parents carry an altered SLC2A1 gene in this recessive form, where early diagnosis supports treatments such as the ketogenic diet and carrier testing in families.
Decoding Juvenile Digenic Hemochromatosis: Genetic Testing for Early Diagnosis and Management
Childhood iron overload can damage the liver, heart and hormone-producing glands; when two genes such as HJV are involved, variant curation guides the diagnosis.
HDL-C QTL10 and the Genetics of HDL Cholesterol
Variation in HDL cholesterol has been mapped to this locus with SNP analysis and genotyping-by-sequencing, methods used to find candidate genes for lipid levels.
Unlocking the Mysteries of Hyperalphalipoproteinemia 1: Genetic Testing for Diagnosis and Management
Discover the potential of genetic testing in diagnosing and managing Hyperalphalipoproteinemia 1, a rare disorder with high HDL cholesterol levels. Learn about its genetic basis…