Decoding the Genetic Mysteries of Behavior Disorders
Research on autism spectrum disorder and bipolar disorder points to genes such as ANK3, Shank2 and miR-137, and DNA analysis can support diagnosis or clarify family risk.
Brandon Colby, MD
MD · MBA
Physician specializing in genetic analysis and personalized preventive medicine, and author of Outsmart Your Genes.
About Brandon
Brandon Colby is a physician-expert in the fields of genetic analysis and Personalized Preventive Medicine. He holds an MD from the Mount Sinai School of Medicine, an MBA from Stanford University's Graduate School of Business, and a degree in Genetics from the University of Michigan.
Dr. Colby is the author of the book Outsmart Your Genes and has developed numerous technologies that improve the analysis, interpretation, and actionability of genome sequencing data. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics (ACMG), an Associate of the American College of Preventive Medicine (ACPM), and a member of the National Society of Genetic Counselors (NSGC).
Education
- BA in Genetics with Honors, University of Michigan · 2000
- MD, Mount Sinai School of Medicine · 2004
- MBA, Stanford University Graduate School of Business · 2007
Affiliations & Memberships
- Affiliate Specialist, American College of Medical Genetics and Genomics (ACMG)
- Associate, American College of Preventive Medicine (ACPM)
- Member, National Society of Genetic Counselors (NSGC)
Articles by Brandon Colby, MD are reviewed for accuracy by Sequencing's medical and scientific team. This page is for informational purposes and does not constitute medical advice.
Articles by Brandon
Bone Mineral Density QTL 15 and Osteoporosis Genetics
Forearm bone density in pedigreed baboons mapped to a region matching human chromosome 11q12-13, one strand of the research gathered here on BMD QTL 15.
CMT2P Genes: LRSAM1, SBF1 and MT-ATP6 Variants
Adult-onset weakness, sensory loss and gait changes mark CMT2P, which has been linked to LRSAM1, SBF1 and the m.9185T>C variant in the MT-ATP6 gene.
Demystifying Chromosome 2q23.1 Deletion Syndrome: Understanding, Diagnosing, and Genetic Testing
Roughly one in 4,000 newborns has this deletion, which can bring developmental delay, growth retardation, dysmorphic facial features and sleep problems.
Genetic Testing for Colorectal Cancer Risk Reduction
Unified testing for polyposis and nonpolyposis syndromes raised diagnostic yield in a Swedish study, and work on the CRP variant rs1205 and rapamycin resistance goes on.
Colostrum Secretion and Newborn Immunity: Genetic Factors
The first milk, colostrum carries antibodies and growth factors that support a newborn's immune system. Genetic testing can detect bacteria and antibiotic resistance.
Unlocking the Mysteries of Congenital Blindness: Genetic Testing and Beyond
Sight loss present from birth can come from several genes: testing distinguishes CSNB, Usher syndrome and Aland Island Eye Disease, including CACNA1F variants.
Congenital Hemolytic Anemia and Its Genetic Causes
Premature red cell destruction brings fatigue, pallor, jaundice and spleen enlargement; exome sequencing can find ATP11C or COL4A1 mutations behind unexplained cases.