Decoding Delta-Plus-Thalassemia: Genetic Testing and Its Significance
Both beta and delta globin genes carry mutations here, producing abnormal hemoglobin; anemia, jaundice and an enlarged spleen may appear, and CBC can mislead.
Brandon Colby, MD
MD · MBA
Physician specializing in genetic analysis and personalized preventive medicine, and author of Outsmart Your Genes.
About Brandon
Brandon Colby is a physician-expert in the fields of genetic analysis and Personalized Preventive Medicine. He holds an MD from the Mount Sinai School of Medicine, an MBA from Stanford University's Graduate School of Business, and a degree in Genetics from the University of Michigan.
Dr. Colby is the author of the book Outsmart Your Genes and has developed numerous technologies that improve the analysis, interpretation, and actionability of genome sequencing data. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics (ACMG), an Associate of the American College of Preventive Medicine (ACPM), and a member of the National Society of Genetic Counselors (NSGC).
Education
- BA in Genetics with Honors, University of Michigan · 2000
- MD, Mount Sinai School of Medicine · 2004
- MBA, Stanford University Graduate School of Business · 2007
Affiliations & Memberships
- Affiliate Specialist, American College of Medical Genetics and Genomics (ACMG)
- Associate, American College of Preventive Medicine (ACPM)
- Member, National Society of Genetic Counselors (NSGC)
Articles by Brandon Colby, MD are reviewed for accuracy by Sequencing's medical and scientific team. This page is for informational purposes and does not constitute medical advice.
Articles by Brandon
Decoding Delta Thalassemia: Understanding, Diagnosing, and Utilizing Genetic Testing
Discover the importance of genetic testing in diagnosing Delta Thalassemia, guiding treatment options, and understanding disease severity. Learn about carrier screening and…
Decoding Delta-Zero-Thalassemia, Knossos Type: Understanding, Diagnosing, and Genetic Testing
One deletion in the HBB gene cuts beta-globin production and unbalances the globin chains; electrophoresis and molecular testing confirm this subtype.
Decoding Developmental Delay: Genetic Testing Unveils the Path to Understanding and Diagnosis
Whole-exome sequencing with copy number analysis found genetic causes in 58.8% of 17 children with developmental delay; GNB1, NAA10 and CUX1 are covered.
Unraveling the Mystery of Diffuse Mesangial Sclerosis: Genetic Testing and Beyond
Discover the benefits of genetic testing for diagnosing Diffuse Mesangial Sclerosis (DMS), a rare kidney disease, and how it aids in early detection, treatment, and family…
Unlocking the Mysteries of Dilated Left Ventricle: A Comprehensive Guide
Discover the role of genetic testing in identifying dilated left ventricle risk factors, understanding sex differences, and improving early detection for better treatment outcomes.
Distal Muscle Weakness: PIEZO2, MATR3 and MPZ
Weakness in the hands and feet can trace back to recessive PIEZO2 mutations, the p.S85C MATR3 variant or a novel MPZ change seen in Charcot-Marie-Tooth disease.
Decoding the Dizygotic Twins Enigma: Understanding and Diagnosing Through Genetic Testing
Discover the role of genetics in dizygotic twins' health, how genetic testing aids in diagnosing diseases, and the impact of genetic factors on various disorders.