MD · MBA
Physician specializing in genetic analysis and personalized preventive medicine, and author of Outsmart Your Genes.
Brandon Colby is a physician-expert in the fields of genetic analysis and Personalized Preventive Medicine. He holds an MD from the Mount Sinai School of Medicine, an MBA from Stanford University's Graduate School of Business, and a degree in Genetics from the University of Michigan.
Dr. Colby is the author of the book Outsmart Your Genes and has developed numerous technologies that improve the analysis, interpretation, and actionability of genome sequencing data. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics (ACMG), an Associate of the American College of Preventive Medicine (ACPM), and a member of the National Society of Genetic Counselors (NSGC).
Articles by Brandon Colby, MD are reviewed for accuracy by Sequencing's medical and scientific team. This page is for informational purposes and does not constitute medical advice.
Seizures continue despite several anti-seizure medicines in about 30% of people with epilepsy. KCNQ2, POLG and ABCB11 variants are among the genetic causes.
Studies tie Cited1, RMND1 and SLC34A1 to kidney dysfunction, and PHACTR1, PPARD and PRKN polymorphisms to treatment-resistant hypertension in chronic kidney disease.
Tumor genetics shape care in renal TCC, also called clear cell renal cell carcinoma, where MYH9 acts as a prognostic marker and a factor in sunitinib resistance.
Progressive deterioration of the retina is studied through canine PRA models and a CNGB1 frameshift mutation, with testing offering diagnosis, prognosis and planning.
Weakened Rh antigen expression can leave routine blood typing inconclusive. Molecular genotyping, serological testing and uses in pregnancy and transfusion are covered.
Peripheral nerves that carry touch, temperature, pain and movement signals degenerate over time. Reported causes include HINT1, TTR and NUDT2 gene variants.
A short fetal femur may reflect normal variation, skeletal dysplasia or chromosomal changes; isolated cases are tied to low birth weight and preterm birth.
Discover the role of genetic testing in diagnosing & managing sickle cell-Hemoglobin O Arab disease, its importance in early detection, treatment guidance, & prenatal care.