Decoding Myokymia 1 with Hypomagnesemia: The Power of Genetic Testing
Low blood magnesium alongside muscle twitching, cramps and weakness marks myokymia 1 with hypomagnesemia, linked to CaSR, CNNM2 and HNF1B variants.
Brandon Colby, MD
MD · MBA
Physician specializing in genetic analysis and personalized preventive medicine, and author of Outsmart Your Genes.
About Brandon
Brandon Colby is a physician-expert in the fields of genetic analysis and Personalized Preventive Medicine. He holds an MD from the Mount Sinai School of Medicine, an MBA from Stanford University's Graduate School of Business, and a degree in Genetics from the University of Michigan.
Dr. Colby is the author of the book Outsmart Your Genes and has developed numerous technologies that improve the analysis, interpretation, and actionability of genome sequencing data. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics (ACMG), an Associate of the American College of Preventive Medicine (ACPM), and a member of the National Society of Genetic Counselors (NSGC).
Education
- BA in Genetics with Honors, University of Michigan · 2000
- MD, Mount Sinai School of Medicine · 2004
- MBA, Stanford University Graduate School of Business · 2007
Affiliations & Memberships
- Affiliate Specialist, American College of Medical Genetics and Genomics (ACMG)
- Associate, American College of Preventive Medicine (ACPM)
- Member, National Society of Genetic Counselors (NSGC)
Articles by Brandon Colby, MD are reviewed for accuracy by Sequencing's medical and scientific team. This page is for informational purposes and does not constitute medical advice.
Articles by Brandon
Neurodevelopmental Abnormalities: Genetic Causes and Testing
Autism spectrum disorder, ADHD, intellectual disability and learning disorders are covered, with PPP2R5D variants and copy number variations found by sequencing.
Decoding Noncompaction Cardiomyopathy: Understanding, Diagnosing, and the Role of Genetic Testing
Spongy, heavily trabeculated heart muscle raises the risk of heart failure, arrhythmia and clots; echocardiography, MRI and sarcomere gene testing identify NCCM.
Noonan-like Syndrome: RASopathy Features and Testing
RAS/MAPK pathway mutations tie this group of disorders to CFC, Costello and LEOPARD syndromes. Facial features, heart defects and skin findings aid the diagnosis.
Decoding the Enigma: Understanding Noonan Syndrome-Like Disorder with Juvenile Myelomonocytic Leukemia
JMML, an aggressive leukemia of young children, can accompany a Noonan syndrome-like phenotype. Blood counts, bone marrow study and DNA sequencing are described.
Decoding Obesity: Understanding, Diagnosing, and Using Genetic Testing
Syndromic forms such as Prader-Willi and Bardet-Biedl sit alongside nonsyndromic obesity among the 550-plus obesity-related single genes identified by researchers.
Decoding the Genetics of Early-Onset Obesity: A Comprehensive Guide
Three genetic routes to obesity that starts in childhood are compared: single genes such as NPY and GPR26, syndromic CNVs, and polygenic risk that includes FTO.
Decoding the Mysteries of Oculocutaneous Albinism Type II: A Guide to Understanding, Diagnosing, and Genetic Testing
Discover Oculocutaneous Albinism Type II (OCA2) - a genetic disorder affecting pigmentation. Learn about diagnosis, genetic testing, and advancements in OCA2 research.