MD · MBA
Physician specializing in genetic analysis and personalized preventive medicine, and author of Outsmart Your Genes.
Brandon Colby is a physician-expert in the fields of genetic analysis and Personalized Preventive Medicine. He holds an MD from the Mount Sinai School of Medicine, an MBA from Stanford University's Graduate School of Business, and a degree in Genetics from the University of Michigan.
Dr. Colby is the author of the book Outsmart Your Genes and has developed numerous technologies that improve the analysis, interpretation, and actionability of genome sequencing data. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics (ACMG), an Associate of the American College of Preventive Medicine (ACPM), and a member of the National Society of Genetic Counselors (NSGC).
Articles by Brandon Colby, MD are reviewed for accuracy by Sequencing's medical and scientific team. This page is for informational purposes and does not constitute medical advice.
Discover the role of genetic testing in sprinting performance, its benefits for athletes and coaches, and how it can optimize training, nutrition, and injury prevention strategies.
Discover the role of genetics in hangover susceptibility, how genetic testing can aid in personalized prevention strategies, and promote responsible alcohol consumption.
Deposits of immunoglobulin A inflame the glomeruli in IgA nephropathy; cited studies point to an aldosterone synthase polymorphism and a susceptibility locus at 2q36.
Certain MBL2 gene variants have been linked to hospital admissions for infection in people with SLE; the page explains testing, dosing adjustments and anifrolumab.
Discover Tay-Sachs Disease diagnosis, genetic testing for carriers & prenatal screening, and explore future treatment options like gene therapy and CRISPR-Cas-9.
Some benign thyroid adenomas overproduce hormones, causing hyperthyroidism. TSH tests and imaging aid diagnosis; BCL-2, CTLA-4 and Fas variants are linked to risk.
TNF receptors steer inflammation and cell survival, so altered binding is tied to autoimmune disease and cancer. TNFRSF1A mutations, for example, cause TRAPS.
SALL1 changes disrupt ear, thumb and kidney development, leading to malformed ears, anal atresia and hearing loss. Testing confirms the diagnosis and guides prognosis.