Progressive Ventriculomegaly in the Fetus: Tests and Genes
Enlarging fetal ventricles show on prenatal ultrasound and MRI, and chromosomal microarray, with exome sequencing in some studies, looks for genetic causes.
Brandon Colby, MD
MD · MBA
Physician specializing in genetic analysis and personalized preventive medicine, and author of Outsmart Your Genes.
About Brandon
Brandon Colby is a physician-expert in the fields of genetic analysis and Personalized Preventive Medicine. He holds an MD from the Mount Sinai School of Medicine, an MBA from Stanford University's Graduate School of Business, and a degree in Genetics from the University of Michigan.
Dr. Colby is the author of the book Outsmart Your Genes and has developed numerous technologies that improve the analysis, interpretation, and actionability of genome sequencing data. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics (ACMG), an Associate of the American College of Preventive Medicine (ACPM), and a member of the National Society of Genetic Counselors (NSGC).
Education
- BA in Genetics with Honors, University of Michigan · 2000
- MD, Mount Sinai School of Medicine · 2004
- MBA, Stanford University Graduate School of Business · 2007
Affiliations & Memberships
- Affiliate Specialist, American College of Medical Genetics and Genomics (ACMG)
- Associate, American College of Preventive Medicine (ACPM)
- Member, National Society of Genetic Counselors (NSGC)
Articles by Brandon Colby, MD are reviewed for accuracy by Sequencing's medical and scientific team. This page is for informational purposes and does not constitute medical advice.
Articles by Brandon
Unlocking the Mystery of Proximal Muscle Weakness in Upper Limbs
In the upper limbs, proximal muscle weakness may have neurological, muscular or skeletal causes, including cervical spinal cord herniation. EMG aids diagnosis.
Decoding Dexfenfluramine-Associated Pulmonary Hypertension: A Guide to Genetic Testing
An appetite suppressant later pulled from the market, dexfenfluramine was linked to raised pulmonary artery pressure found on echocardiography and heart catheterization.
Decoding the Mysteries of Fenfluramine-Associated Pulmonary Hypertension: Genetic Testing for Diagnosis and Management
Symptoms of FAPH overlap with other heart and lung conditions, so testing for pulmonary hypertension variants, including novel VARS2 findings, helps clarify risk.
Blood Group Antigens: ABO Genetics and Disease Risk
Antigens on red blood cells have been studied for links to COVID-19 and rotavirus, and a 24-base pair deletion in ABO can produce blood group O.
MTTP Polymorphism: Lipid Metabolism and Heart Risk
Variants in the MTTP gene alter how lipoproteins are assembled, affecting lipid handling and cardiovascular risk. Testing can guide lipid-lowering treatment choices.
Decoding the Mystery of Distal Renal Tubular Acidosis: A Guide to Understanding, Diagnosing, and Genetic Testing
Acid builds up when the distal renal tubules cannot excrete it, bringing kidney stones, bone disease and hypokalemia; SLC4A1 variants and alkali therapy are covered.
Unlocking the Mystery of Rh-null: The Regulator Type Blood Phenotype
Discover the importance of genetic testing in diagnosing and managing Rh-null, regulator type blood phenotype, its treatment, and blood transfusion compatibility.