Decoding the Genetic Mysteries of Malaria Susceptibility
Variation in the CSF2 gene has been tied to pediatric malaria, severe malarial anemia and mortality in Kenya, and genome-wide studies keep adding risk factors.
Brandon Colby, MD
MD · MBA
Physician specializing in genetic analysis and personalized preventive medicine, and author of Outsmart Your Genes.
About Brandon
Brandon Colby is a physician-expert in the fields of genetic analysis and Personalized Preventive Medicine. He holds an MD from the Mount Sinai School of Medicine, an MBA from Stanford University's Graduate School of Business, and a degree in Genetics from the University of Michigan.
Dr. Colby is the author of the book Outsmart Your Genes and has developed numerous technologies that improve the analysis, interpretation, and actionability of genome sequencing data. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics (ACMG), an Associate of the American College of Preventive Medicine (ACPM), and a member of the National Society of Genetic Counselors (NSGC).
Education
- BA in Genetics with Honors, University of Michigan · 2000
- MD, Mount Sinai School of Medicine · 2004
- MBA, Stanford University Graduate School of Business · 2007
Affiliations & Memberships
- Affiliate Specialist, American College of Medical Genetics and Genomics (ACMG)
- Associate, American College of Preventive Medicine (ACPM)
- Member, National Society of Genetic Counselors (NSGC)
Articles by Brandon Colby, MD are reviewed for accuracy by Sequencing's medical and scientific team. This page is for informational purposes and does not constitute medical advice.
Articles by Brandon
Decoding the Mystery of Microphthalmia, Cataracts, and Iris Abnormalities: The Role of Genetic Testing
Reports link PRR12 haploinsufficiency, biallelic CTNNB1 variants, paired GJA8 and CRYGC changes and a PAX6 deletion to small eyes, cataracts and aniridia.
Familial Basilar Migraine: Aura Symptoms and Gene Tests
Vertigo, double vision, loss of balance and brainstem aura mark this autosomal dominant migraine; CACNA1A and MYORG findings show what gene analysis can add.
Unlocking the Mystery of Moderate Global Developmental Delay: Genetic Testing and Beyond
Discover the role of genetic testing in diagnosing moderate global developmental delay, unlocking underlying causes, and guiding targeted treatment options for improved outcomes.
Decoding the Roots of Morbid Obesity: A Deeper Look into Genetic Testing
Discover the role of genetic testing in diagnosing morbid obesity, guiding personalized treatment plans, and exploring emerging therapies for a healthier life.
Decoding Mucolipidosis III Alpha/Beta: A Comprehensive Guide to Genetic Testing and Diagnosis
Pathogenic variants in GNPTAB remove the mannose-6-phosphate tag that directs enzymes to lysosomes, causing skeletal and joint problems; NGS confirms the diagnosis.
Decoding the Genetic Secrets of Mycobacterium Tuberculosis: Protection and Severity
The IL-17A rs2275913 AA genotype and the CD209 -336G allele have been linked to protection against active tuberculosis in the studies summarized on this page.
Decoding the Genetic Mysteries of Centronuclear Myopathy Type 2
DNM2 changes cause the muscle weakness and wasting of CNM2, with SPEG, BIN1 and MTM1 mutations also reported, widening what genetic testing can detect.