Genetic Causes of Death in Infancy: Testing Options
Infant mortality is driven partly by genetic disorders that go under-recorded; MCADD, GACI and the ENPP1 gene show how molecular autopsy and sequencing help.
Brandon Colby, MD
MD · MBA
Physician specializing in genetic analysis and personalized preventive medicine, and author of Outsmart Your Genes.
About Brandon
Brandon Colby is a physician-expert in the fields of genetic analysis and Personalized Preventive Medicine. He holds an MD from the Mount Sinai School of Medicine, an MBA from Stanford University's Graduate School of Business, and a degree in Genetics from the University of Michigan.
Dr. Colby is the author of the book Outsmart Your Genes and has developed numerous technologies that improve the analysis, interpretation, and actionability of genome sequencing data. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics (ACMG), an Associate of the American College of Preventive Medicine (ACPM), and a member of the National Society of Genetic Counselors (NSGC).
Education
- BA in Genetics with Honors, University of Michigan · 2000
- MD, Mount Sinai School of Medicine · 2004
- MBA, Stanford University Graduate School of Business · 2007
Affiliations & Memberships
- Affiliate Specialist, American College of Medical Genetics and Genomics (ACMG)
- Associate, American College of Preventive Medicine (ACPM)
- Member, National Society of Genetic Counselors (NSGC)
Articles by Brandon Colby, MD are reviewed for accuracy by Sequencing's medical and scientific team. This page is for informational purposes and does not constitute medical advice.
Articles by Brandon
Decoding Dengue: Understanding, Diagnosing, and Using Genetic Testing for Dengue Fever Protection
African ancestry has been linked to protection from dengue hemorrhagic fever through OSBPL10 and RXRA; Aedes aegypti genetics also shapes vector control.
Unraveling the Mystery: Understanding and Diagnosing Type 1 Diabetes Susceptibility
Variation in the MHC region shapes susceptibility to type 1 diabetes, while chemicals and the bacterium MAP have been studied as environmental triggers.
Decoding the Genetic Mysteries of Type 2 Diabetes Susceptibility
Polymorphism studies of IL-6 rs1800796, CDKAL1, GRB10 rs1800504 and TCF7L2 rs12255372 show which variants track with type 2 diabetes risk and which do not.
Decoding the Broad Bone-Platyspondylic Variant of Diastrophic Dysplasia: Genetic Testing for Diagnosis and Management
Wide, flattened spinal bones and other skeletal changes mark this variant, which follows mutations in the DTDST gene that molecular analysis can confirm.
Decoding the Genetic Mysteries of Dilated Cardiomyopathy with Left Ventricular Noncompaction
Noncompaction of the left ventricular myocardium alongside dilated ventricles affects children and adults; echocardiography, MRI and DNA analysis help confirm it.
Decoding Early Onset Alzheimer's Disease with Behavioral Disturbance: A Genetic Perspective
Cognitive decline with early psychiatric symptoms can begin as young as 40; the PSEN1 Thr119Ile mutation, an APP duplication and mild behavioral impairment are discussed.
Decoding Ectodermal Dysplasia 10a: Understanding, Diagnosing, and Harnessing the Power of Genetic Testing
HED affects sweat glands, hair and teeth, causing reduced sweating, missing teeth and sparse hair. Genetic testing can confirm it and identify carriers.