What Genes and Air Pollution Mean for Psoriasis Risk
Air pollutant exposure and inherited variants such as NLRP3 both appear in psoriasis research, alongside testing used to gauge risk and predict treatment response.
Brandon Colby, MD
MD · MBA
Physician specializing in genetic analysis and personalized preventive medicine, and author of Outsmart Your Genes.
About Brandon
Brandon Colby is a physician-expert in the fields of genetic analysis and Personalized Preventive Medicine. He holds an MD from the Mount Sinai School of Medicine, an MBA from Stanford University's Graduate School of Business, and a degree in Genetics from the University of Michigan.
Dr. Colby is the author of the book Outsmart Your Genes and has developed numerous technologies that improve the analysis, interpretation, and actionability of genome sequencing data. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics (ACMG), an Associate of the American College of Preventive Medicine (ACPM), and a member of the National Society of Genetic Counselors (NSGC).
Education
- BA in Genetics with Honors, University of Michigan · 2000
- MD, Mount Sinai School of Medicine · 2004
- MBA, Stanford University Graduate School of Business · 2007
Affiliations & Memberships
- Affiliate Specialist, American College of Medical Genetics and Genomics (ACMG)
- Associate, American College of Preventive Medicine (ACPM)
- Member, National Society of Genetic Counselors (NSGC)
Articles by Brandon Colby, MD are reviewed for accuracy by Sequencing's medical and scientific team. This page is for informational purposes and does not constitute medical advice.
Articles by Brandon
Decoding Renal Cell Carcinoma with Paraneoplastic Erythrocytosis: Diagnosis and Genetic Testing
Discover the role of genetic testing in diagnosing and treating renal cell carcinoma with paraneoplastic erythrocytosis, a rare kidney cancer manifestation.
Understanding Retinal Arterial Macroaneurysm with Supravascular Pulmonic Stenosis
Macroaneurysms in the retinal arteries and a narrowed pulmonary valve define RAMSPS; dilated eye exams, echocardiography and DNA analysis are used to confirm it.
Rhabdomyosarcoma (RMS): Somatic Mutations and Testing
The most common soft tissue sarcoma in children also occurs in adults. Reported findings include a KRAS mutation with somatic mosaicism, plus testing for prognosis.
Demystifying Autosomal Recessive Rippling Muscle Disease 2: Genetic Testing and Its Benefits
Discover Autosomal Recessive Rippling Muscle Disease 2 (RMD2), its diagnosis, and the importance of genetic testing in managing this rare genetic disorder.
Demystifying Schwannomatosis 1: Genetic Testing and Its Significance
Multiple noncancerous schwannomas grow along peripheral nerves, causing pain, numbness and weakness in adults. MRI, biopsy and gene testing confirm the diagnosis.
Unraveling the Mystery of Mild Septooptic Dysplasia: Genetic Testing for Diagnosis and Management
Optic nerve, pituitary and midline brain development are affected in this congenital disorder, and testing HESX1, SOX2 and OTX2 can confirm milder presentations.
Decoding the Mystery of Severe Sensorineural Hearing Impairment: A Comprehensive Guide
Damage to the cochlea or auditory nerve can be inherited: TECTA variants cause DFNA8/12 and MT-RNR1 variants have been reported, alongside audiometry and imaging.