MD · MBA
Physician specializing in genetic analysis and personalized preventive medicine, and author of Outsmart Your Genes.
Brandon Colby is a physician-expert in the fields of genetic analysis and Personalized Preventive Medicine. He holds an MD from the Mount Sinai School of Medicine, an MBA from Stanford University's Graduate School of Business, and a degree in Genetics from the University of Michigan.
Dr. Colby is the author of the book Outsmart Your Genes and has developed numerous technologies that improve the analysis, interpretation, and actionability of genome sequencing data. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics (ACMG), an Associate of the American College of Preventive Medicine (ACPM), and a member of the National Society of Genetic Counselors (NSGC).
Articles by Brandon Colby, MD are reviewed for accuracy by Sequencing's medical and scientific team. This page is for informational purposes and does not constitute medical advice.
Discover the importance of understanding neutrophil inclusion bodies in diagnosing MYH9-related disorders and how genetic testing can guide treatment, inform family planning, and…
No sperm reaches the ejaculate because production in the testes is impaired, affecting about 1% of men. Karyotypes, Y microdeletions and MSH4 variants are discussed.
Discover the benefits of genetic testing for oligodontia, a rare dental condition, to ensure accurate diagnosis, personalized treatment, and better family planning.
Benign growth of fibrous tissue and bone in the jaw can cause facial deformity and chewing difficulty; CDC73 mutations link ossifying fibroma to HPT-JT syndrome.
Finger-like papillary structures mark ovarian papillary adenocarcinoma, often found late; BRCA1/2 and BRCAness results inform PARP inhibitor and surgery decisions.
Night blindness and lost peripheral vision mark this inherited retinal degeneration, which can occur with Bardet-Biedl, Kearns-Sayre and Usher syndromes.
Faulty DNA proofreading lets replication errors build up, and this POLE alteration appears in colorectal and endometrial cancers with very high tumor mutation burden.
From Alpers-Huttenlocher syndrome to recessive progressive external ophthalmoplegia, these conditions are confirmed by POLG analysis, which also identifies carriers.