Understanding, Diagnosing, and Using Genetic Testing for Sex Cord-Stromal Tumor
Arising from the supporting tissue of the ovaries or testes, these rare tumors include granulosa cell and Sertoli-Leydig types, with FOXL2 mutations seen in some.
Brandon Colby, MD
MD · MBA
Physician specializing in genetic analysis and personalized preventive medicine, and author of Outsmart Your Genes.
About Brandon
Brandon Colby is a physician-expert in the fields of genetic analysis and Personalized Preventive Medicine. He holds an MD from the Mount Sinai School of Medicine, an MBA from Stanford University's Graduate School of Business, and a degree in Genetics from the University of Michigan.
Dr. Colby is the author of the book Outsmart Your Genes and has developed numerous technologies that improve the analysis, interpretation, and actionability of genome sequencing data. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics (ACMG), an Associate of the American College of Preventive Medicine (ACPM), and a member of the National Society of Genetic Counselors (NSGC).
Education
- BA in Genetics with Honors, University of Michigan · 2000
- MD, Mount Sinai School of Medicine · 2004
- MBA, Stanford University Graduate School of Business · 2007
Affiliations & Memberships
- Affiliate Specialist, American College of Medical Genetics and Genomics (ACMG)
- Associate, American College of Preventive Medicine (ACPM)
- Member, National Society of Genetic Counselors (NSGC)
Articles by Brandon Colby, MD are reviewed for accuracy by Sequencing's medical and scientific team. This page is for informational purposes and does not constitute medical advice.
Articles by Brandon
Understanding, Diagnosing, and Using Genetic Testing for Somatotroph Adenoma
Excess growth hormone from somatotroph adenomas, benign pituitary tumors, can cause acromegaly or gigantism. MRI, IGF-1 and AIP gene testing aid diagnosis.
Understanding Spastic Ataxia 1: Diagnosis and Genetic Testing
Clinical evaluation, MRI of the brain and spinal cord, and testing for the p.Glu415Lys variant in the TUBA4A gene are the steps used to confirm SA1.
Understanding, Diagnosing, and Using Genetic Testing for Spermatogenic Failure 2
Semen analysis, hormone tests for FSH, LH and testosterone, and karyotyping for Klinefelter syndrome or AZF microdeletions build the diagnostic picture in SPGF2.
Stickler Syndrome Type 1 and the COL2A1 Gene
Mutations in COL2A1 disrupt type II collagen in Stickler syndrome type 1, causing severe myopia, hearing loss, joint pain and craniofacial changes such as cleft palate.
What Causes Subvalvular Aortic Stenosis? Tests and Genes
Narrowing below the aortic valve makes the heart work harder, causing chest pain, breathlessness and fainting; echocardiography, ECG and cardiac MRI help assess SAS.
Understanding, Diagnosing, and Utilizing Genetic Testing for Systolic Heart Failure
When the left ventricle cannot contract strongly enough, breathlessness and fluid retention follow. Echocardiogram, ECG and TTN gene testing help explain the cause.
Understanding, Diagnosing, and Using Genetic Testing for Thoracic Aortic Aneurysm
A weakened section of the upper aorta may stay silent until it is large; CT, MRI and echocardiography size it, while Marfan and Loeys-Dietz syndromes raise risk.