Understanding, Diagnosing, and Using Genetic Testing for Adrenal Cortex Carcinoma
Weight gain, high blood pressure and hormonal imbalance can be the first clues to adrenal cortex carcinoma; germline TP53 findings help shape treatment decisions.
Brandon Colby, MD
MD · MBA
Physician specializing in genetic analysis and personalized preventive medicine, and author of Outsmart Your Genes.
About Brandon
Brandon Colby is a physician-expert in the fields of genetic analysis and Personalized Preventive Medicine. He holds an MD from the Mount Sinai School of Medicine, an MBA from Stanford University's Graduate School of Business, and a degree in Genetics from the University of Michigan.
Dr. Colby is the author of the book Outsmart Your Genes and has developed numerous technologies that improve the analysis, interpretation, and actionability of genome sequencing data. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics (ACMG), an Associate of the American College of Preventive Medicine (ACPM), and a member of the National Society of Genetic Counselors (NSGC).
Education
- BA in Genetics with Honors, University of Michigan · 2000
- MD, Mount Sinai School of Medicine · 2004
- MBA, Stanford University Graduate School of Business · 2007
Affiliations & Memberships
- Affiliate Specialist, American College of Medical Genetics and Genomics (ACMG)
- Associate, American College of Preventive Medicine (ACPM)
- Member, National Society of Genetic Counselors (NSGC)
Articles by Brandon Colby, MD are reviewed for accuracy by Sequencing's medical and scientific team. This page is for informational purposes and does not constitute medical advice.
Articles by Brandon
ADULT Syndrome (TP63): Signs, Diagnosis and Testing
Acro-Dermato-Ungual-Lacrimal-Tooth syndrome involves hand and foot malformations, nail dystrophy, dental anomalies and tear duct problems caused by TP63 mutations.
Understanding, Diagnosing, and Using Genetic Testing for Alcohol Dependence
Cravings, loss of control, withdrawal and tolerance are assessed with tools such as AUDIT, while variants in GABA, dopamine and serotonin genes shape drug response.
Understanding, Diagnosing, and Using Genetic Testing for Alternating Hemiplegia of Childhood 1
Recurrent hemiplegia that alternates sides, along with dystonia, ataxia and developmental delays, points to AHC1; exome sequencing or a gene panel checks ATP1A3.
Understanding, Diagnosing, and Using Genetic Testing for Alzheimer Disease Type 1
Amyloid-beta plaques and neurofibrillary tangles define AD1; diagnosis draws on cognitive tests, MRI or PET, biomarkers and DNA analysis of APP, PSEN1 and PSEN2.
Understanding, Diagnosing, and Using Genetic Testing for Amelogenesis Imperfecta - Hypoplastic Autosomal Dominant - Local
Amelogenesis Imperfecta hypoplastic type impacts enamel thickness. Genetic testing confirms diagnosis and aids in family planning and personalized treatments.
Understanding, Diagnosing, and Using Genetic Testing for Amelogenesis Imperfecta Type 1A
Thin, decay-prone teeth follow enamel that is both hypomineralized and hypoplastic; a novel AMELX intron variant was found in female patients from two families.
Understanding and Diagnosing Amyloidogenic Transthyretin Amyloidosis: The Role of Genetic Testing
Misfolded transthyretin forms amyloid fibrils that settle in the heart, kidneys and nerves, causing neuropathy, cardiomyopathy and gastrointestinal symptoms.