MD · MBA
Physician specializing in genetic analysis and personalized preventive medicine, and author of Outsmart Your Genes.
Brandon Colby is a physician-expert in the fields of genetic analysis and Personalized Preventive Medicine. He holds an MD from the Mount Sinai School of Medicine, an MBA from Stanford University's Graduate School of Business, and a degree in Genetics from the University of Michigan.
Dr. Colby is the author of the book Outsmart Your Genes and has developed numerous technologies that improve the analysis, interpretation, and actionability of genome sequencing data. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics (ACMG), an Associate of the American College of Preventive Medicine (ACPM), and a member of the National Society of Genetic Counselors (NSGC).
Articles by Brandon Colby, MD are reviewed for accuracy by Sequencing's medical and scientific team. This page is for informational purposes and does not constitute medical advice.
CDH1 mutations, and less often TP53, drive HDGC, a cancer that spreads through the stomach lining; sequencing can identify carriers before cancer develops.
Red cells take a sphere shape when membrane proteins are faulty, causing anemia, jaundice and an enlarged spleen. Genetic and imaging tests pin down the cause.
Part of the stomach pushes through the diaphragm in either a sliding or paraesophageal form, with heartburn, regurgitation and swallowing difficulty as symptoms.
Unravel Hidrotic Ectodermal Dysplasia Syndrome with genetic testing. Gain accurate diagnosis, personalized care, and informed family planning insights.
Autosomal dominant inheritance means one altered copy causes this hip disorder, which brings early-onset pain and reduced mobility beginning in childhood.
Several genes contribute to this bowel condition, but testing has limits: a study of southern Chinese children found no link with the PCSK2 SNP rs16998727.
Mutations in Sonic Hedgehog signaling disturb midline development, and newer work points to gene modifiers acting alongside the known driver mutations.
Failure of the forebrain to split into two hemispheres produces craniofacial and neurological effects, and carrier status informs recurrence risk in later pregnancies.