Advanced Sleep Phase Syndrome 2: Unlocking the Genetic Code for Better Sleep
Falling asleep in the early evening and waking very early often runs in families; ASPS2 has been linked to a mutation at an hPer2 phosphorylation site.
Brandon Colby, MD
MD · MBA
Physician specializing in genetic analysis and personalized preventive medicine, and author of Outsmart Your Genes.
About Brandon
Brandon Colby is a physician-expert in the fields of genetic analysis and Personalized Preventive Medicine. He holds an MD from the Mount Sinai School of Medicine, an MBA from Stanford University's Graduate School of Business, and a degree in Genetics from the University of Michigan.
Dr. Colby is the author of the book Outsmart Your Genes and has developed numerous technologies that improve the analysis, interpretation, and actionability of genome sequencing data. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics (ACMG), an Associate of the American College of Preventive Medicine (ACPM), and a member of the National Society of Genetic Counselors (NSGC).
Education
- BA in Genetics with Honors, University of Michigan · 2000
- MD, Mount Sinai School of Medicine · 2004
- MBA, Stanford University Graduate School of Business · 2007
Affiliations & Memberships
- Affiliate Specialist, American College of Medical Genetics and Genomics (ACMG)
- Associate, American College of Preventive Medicine (ACPM)
- Member, National Society of Genetic Counselors (NSGC)
Articles by Brandon Colby, MD are reviewed for accuracy by Sequencing's medical and scientific team. This page is for informational purposes and does not constitute medical advice.
Articles by Brandon
Agammaglobulinemia 7, Autosomal Recessive: Unveiling the Genetic Mysteries
Two copies of a faulty gene are needed for this immunoglobulin deficiency to appear; PIK3R1 sequencing supports early diagnosis, carrier screening and treatment.
Analyzing Amyotrophic Lateral Sclerosis Type 20: The Role of Genetic Testing
Unlike sporadic ALS, type 20 has a genetic basis often tied to the SOD1 gene, so testing can flag risk before symptoms and inform relatives' decisions.
How Ataxia with Oculomotor Apraxia Type 3 Is Diagnosed
Coordination, eye movement and nerve problems begin in early adulthood in AOA3, and DNA analysis of SETX and related genes confirms what symptoms alone cannot.
Understanding Autism, Susceptibility to, 18: The Role of Genetic Testing
CHD8 mutations disturb chromatin remodeling and have been linked to autism with macrocephaly, gastrointestinal problems and developmental delay in a case report.
Understanding Autism Susceptibility 19: The Role of Genetic Testing
Rather than a single gene, this locus emerged from genome-wide association studies as one of many genome regions tied to autism risk, monitoring and counseling.
A Deep Dive into Autosomal Dominant Hypocalcemia 2: The Genetic Testing Revolution
Low blood calcium in ADH2 traces back to changes in the GNA11 gene. Cramps, spasms and seizures, and what a confirmed diagnosis means for families, are covered.
Addressing Autosomal Recessive Congenital Ichthyosis 10: The Role of Genetic Testing
Thick, plate-like scales with redness and inflammation characterize ARCI10, a form of lamellar ichthyosis managed with hydration, keratolytics and genetic counseling.