Fathoming Focal Segmental Glomerulosclerosis 9: The Genetic Testing Frontier
Proteinuria and declining kidney function overlap with other disorders; genetic testing can flag FSGS 9 before symptoms appear and steer treatment and counseling.
Brandon Colby, MD
MD · MBA
Physician specializing in genetic analysis and personalized preventive medicine, and author of Outsmart Your Genes.
About Brandon
Brandon Colby is a physician-expert in the fields of genetic analysis and Personalized Preventive Medicine. He holds an MD from the Mount Sinai School of Medicine, an MBA from Stanford University's Graduate School of Business, and a degree in Genetics from the University of Michigan.
Dr. Colby is the author of the book Outsmart Your Genes and has developed numerous technologies that improve the analysis, interpretation, and actionability of genome sequencing data. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics (ACMG), an Associate of the American College of Preventive Medicine (ACPM), and a member of the National Society of Genetic Counselors (NSGC).
Education
- BA in Genetics with Honors, University of Michigan · 2000
- MD, Mount Sinai School of Medicine · 2004
- MBA, Stanford University Graduate School of Business · 2007
Affiliations & Memberships
- Affiliate Specialist, American College of Medical Genetics and Genomics (ACMG)
- Associate, American College of Preventive Medicine (ACPM)
- Member, National Society of Genetic Counselors (NSGC)
Articles by Brandon Colby, MD are reviewed for accuracy by Sequencing's medical and scientific team. This page is for informational purposes and does not constitute medical advice.
Articles by Brandon
FTD/ALS2: UBQLN2 Variants and Early Detection
Families facing FTD/ALS2 can use UBQLN2 testing for earlier detection, treatment planning and genetic counseling, with research noting sex differences.
Genetic Insights into Generalized Epilepsy with Febrile Seizures Plus, Type 9
Twins carrying a GABRB3 mutation show how GEFS+9 starts with febrile seizures in early childhood; in that report levetiracetam controlled the seizures.
Genetic Insights into Glucocorticoid Resistance: A Pathway to Personalized Medicine
Mutations in the glucocorticoid receptor gene blunt the body's response to cortisol, producing fatigue, hypertension and metabolic changes that DNA testing can trace.
Hennekam Lymphangiectasia-Lymphedema Syndrome 2: Harnessing Genetic Testing for Hope and Healing
Reduced ADAMTS3 activity disturbs lymph vessel development, leading to lymphedema, intestinal lymphangiectasia, facial differences and developmental delay.
Harnessing Genetic Insights: Understanding Hyperlipoproteinemia, Type 1D
Eruptive xanthomas, abdominal pain and repeated pancreatitis can follow GPIHBP1 mutations that impair lipoprotein lipase. Testing and monitoring are outlined.
HID5: Epilepsy, Facial Features and GPI Anchors
Disrupted GPI anchor metabolism can bring intellectual disability, epilepsy and distinct facial features in HID5. Diagnosis and the limits of testing are discussed.
Harnessing Genetics: Unraveling Hyperproinsulinemia
Proinsulin builds up when its conversion to insulin falters, a pattern seen with type 2 and gestational diabetes. Genetic markers and risk assessment are covered.