Navigating Nevus Comedonicus Syndrome: Genetic Testing's Role in Diagnosis and Management
Grouped blackhead-like lesions define this rare skin disorder, reported alongside a NEK9 mutation, pulmonary airway malformation and vascular anomalies.
Brandon Colby, MD
MD · MBA
Physician specializing in genetic analysis and personalized preventive medicine, and author of Outsmart Your Genes.
About Brandon
Brandon Colby is a physician-expert in the fields of genetic analysis and Personalized Preventive Medicine. He holds an MD from the Mount Sinai School of Medicine, an MBA from Stanford University's Graduate School of Business, and a degree in Genetics from the University of Michigan.
Dr. Colby is the author of the book Outsmart Your Genes and has developed numerous technologies that improve the analysis, interpretation, and actionability of genome sequencing data. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics (ACMG), an Associate of the American College of Preventive Medicine (ACPM), and a member of the National Society of Genetic Counselors (NSGC).
Education
- BA in Genetics with Honors, University of Michigan · 2000
- MD, Mount Sinai School of Medicine · 2004
- MBA, Stanford University Graduate School of Business · 2007
Affiliations & Memberships
- Affiliate Specialist, American College of Medical Genetics and Genomics (ACMG)
- Associate, American College of Preventive Medicine (ACPM)
- Member, National Society of Genetic Counselors (NSGC)
Articles by Brandon Colby, MD are reviewed for accuracy by Sequencing's medical and scientific team. This page is for informational purposes and does not constitute medical advice.
Articles by Brandon
Orofacial Cleft 15: Unveiling Genetic Insights into a Complex Condition
Rare variants in SEC24D, a gene involved in protein transport within cells, influence how orofacial cleft 15 presents; testing supports earlier diagnosis.
Pinpointing Paget: Genetic Testing's Role in Paget Disease of Bone 6
Disordered bone remodeling leaves bone enlarged, misshapen and prone to fracture, often silently at first; ZNF687 mutations allow screening within affected families.
Piecing Together the Puzzle: Understanding Palatal Anomalies-Widely Spaced Teeth-Facial Dysmorphism-Developmental Delay Syndrome
Cleft palate, widely spaced teeth, distinctive facial features and developmental delay define this rare syndrome, and sequencing can confirm it and clarify inheritance.
Pandemic of Pancytopenia: Understanding the Role of Genetic Testing for IKZF1 Mutations
IKZF1 shapes lymphocyte development, and mutations in it can lower blood cell production, bringing fatigue, infections and bleeding that mimic other blood disorders.
Genetic Testing and Patent Ductus Arteriosus 2: Promising Pathways to Precision Medicine
When the ductus arteriosus fails to close after birth, infants risk heart failure and pulmonary hypertension; exome sequencing seeks candidate genes for PDA2.
Genetic Testing: A Gateway to Understanding Platelet-type Bleeding Disorder 20
Bleeding from minor injuries can reflect hyperactive platelets rather than von Willebrand disease, and GP1BA mutations altering the GPIba receptor define PTBD20.
Polycystic Liver Disease 2: Unlocking the Genetic Code to Better Understand and Manage the Condition
Numerous benign liver cysts can bring abdominal pain and bloating; PLD2 is autosomal dominant, involves PRKCSH and SEC63, and often accompanies polycystic kidney disease.