Chain26: Long QT syndrome

Determine the risk of death caused by long QT syndrone

Relevant info

Understand what predisposes you to sudden death

Example use A

Preventable measures through medication

Example use B

Preventable measures through screening habits

Other uses

Preventable measures through medical devices

Developer

Dr. Colby

Genetic info

Genes	Genetic variants
ANK2	chr4:114269433,chr4:114269433,chr4:114288920,chr4:114294462,chr4:114294318,chr4:114294537,chr4:114286207
KCNQ1	chr11:2604687,chr11:2604663,chr11:2592624,chr11:2593286,chr11:2604765,chr11:2608843,chr11:2610045,chr11:2790133,rs179489,chr11:2591882,chr11:2591945,chr11:2593319,chr11:2594101,chr11:2604683,chr11:2604716,chr11:2798232,chr11:2799245,chr11:2466715,chr11:2604775,chr11:2604780,chr11:2594182
KCNH2	chr7:150671913,chr7:150671819,chr7:150654573,chr7:150649832,chr7:150649763,chr7:150648800,chr7:150648799,chr7:150648671,chr7:150648643,chr7:150648640,chr7:150648599,chr7:150647450,chr7:150646072,chr7:150646069,chr7:150644528,chr7:150642476,chr7:150644415,chr7:150654379,chr7:150648009,chr7:150648703
KCNJ2	chr17:68171403,chr17:68172231
KCNE2	chr21:35743006,chr21:35743124,chr21:35742970,chr21:35742938
CAV3	chr3:8787330,chr3:8787520,chr3:8787350,chr3:8787387
SCN5A	chr3:38597170,chr3:38601909,chr3:38645558,chr3:38674773,chr3:38647543,chr3:38645241,chr3:38640489,chr3:38616876,chr3:38603958,chr3:38601895,chr3:38592995,chr3:38592513,chr3:38592125,chr3:38591990,chr3:38647954
SCN4B	chr11:118011980
KCNE1	chr21:35821779,chr21:35821850,chr21:35821794,chr21:35821707,chr21:35821641,chr21:35821608,chr21:35821554
SNTA1	chr20:31998009

Qualitative

Type

text

Possible responses

Yes, No, Insufficient Data, Error

let appChainsManager = AppChains.init(token: "<YOUR TOKEN HERE>" as String, withHostName: "api.sequencing.com")
 
appChainsManager.getReportWithApplicationMethodName("Chain26", withDatasourceId: "<FILE ID HERE>", withSuccessBlock: { (result) in
            let resultReport: Report = result as Report!
 
            if resultReport.isSucceeded() {   
                if resultReport.getResults() != nil {
                    for item: AnyObject in resultReport.getResults() {
 
                        let resultObj = item as! Result
                        let resultValue: ResultValue = resultObj.getValue()
 
                        if resultValue.getType() == ResultType.Text {
                            print(resultObj.getName() + " = " + (resultValue as! TextResultValue).getData())
                        }
                    }
                }  
            } else {
                print("Error occured while getting genetic information")
            }
 
            }) { (error) in
                print("Error occured while getting genetic information. " + error.localizedDescription)
        }

AppChains *appChains = [[AppChains alloc] initWithToken:@"<YOUR TOKEN HERE>" withHostName:@"api.sequencing.com"];
    
[appChains getReportWithApplicationMethodName:@"Chain26"
		withDatasourceId:@"<FILE ID HERE>"
		withSuccessBlock:^(Report *result) {

			for (Result *obj in [result getResults]) {
				ResultValue *frv = [obj getValue];
				if ([frv getType] == kResultTypeText) {
					NSLog(@"\nvalue %@ = %@\n", [obj getName], [(TextResultValue *)frv getData]);
				}
			}
        }
        withFailureBlock:^(NSError *error) {
        	NSLog(@"Error occured: %@", [error description]);
        }];

AppChains chains = new AppChains("<YOUR TOKEN HERE>", "api.sequencing.com");
Report result = chains.getReport("StartApp", "Chain26", "<FILE ID HERE>");
 
if (result.isSucceeded() == false)
    System.out.println("Request has failed");
else
    System.out.println("Request has succeeded");
 
for (Result r : result.getResults())
{
    ResultType type = r.getValue().getType();
 
    if (type == ResultType.TEXT)
    {
        TextResultValue v = (TextResultValue) r.getValue();
        System.out.println(String.format(" -> text result type %s = %s", r.getName(), v.getData()));
    }
}

my $chains = AppChains->new("<YOUR TOKEN HERE>", "api.sequencing.com");
my $chainsResult = $chains->getReport("StartApp", "Chain26", "<FILE ID HERE>");
 
if ($chainsResult->isSucceeded()) {
    print "Request has succeeded\n";
} else {
    print "Request has failed\n";
}
 
foreach (@{$chainsResult->getResults()})
{
    my $type = $_->getValue()->getType();
 
    if ($type == ResultType->TEXT)
    {
        my $v = $_->getValue();
        print sprintf("-> text result type %s = %s\n", $_->getName(), $v->getData());
    }
}

self.chains = AppChains('<YOUR TOKEN HERE>', 'api.sequencing.com')
chains_result = self.chains.getReport('StartApp', 'Chain26', '<FILE ID HERE>')
if chains_result.isSucceeded():
    print('Request has succeeded')
    else:
        print('Request has failed')
        for r in chains_result.getResults():
            file_type = r.getValue().getType()
            v = r.getValue()
            if file_type == 'TEXT':
                print('-> text result type {} = {}'.format(
                    r.getName(), v.getData()))

$chains = new AppChains("<YOUR TOKEN HERE>", "api.sequencing.com");
$chainsResult = $chains->getReport("StartApp", "Chain26", "<FILE ID HERE>");
 
if ($chainsResult->isSucceeded())
    echo "Request has succeeded\n";
else
    echo "Request has failed\n";
 
foreach ($chainsResult->getResults() as $r)
{
    $type = $r->getValue()->getType();
 
    switch ($type)
    {
        case ResultType::TEXT:
            $v = $r->getValue();
            echo sprintf("-> text result type %s = %s\n", $r->getName(), $v->getData());
        break;
    }
}

var chains = new AppChains("<YOUR TOKEN HERE>", "https://api.sequencing.com/v1", "https://beacon.sequencing.com/");
 
Report result = chains.GetReport("Chain26", "<FILE ID HERE>");
if (result.Succeeded == false)
    Console.WriteLine("Request has failed");
else
    Console.WriteLine("Request has succeeded");
foreach (Result r in result.getResults())
{
    ResultType type = r.getValue().getType();
 
    if (type == ResultType.TEXT)
    {
        var v = (TextResultValue) r.getValue();
        Console.WriteLine(" -> text result type {0} = {1}", r.getName(), v.Data);
    }
}